Results 51 to 60 of about 42,839 (296)

Understanding the Effects of Conductive Polymer Electrode Coating on Recorded Neural Signals

Advanced Healthcare Materials, EarlyView.
Conductive polymer coatings are widely explored to improve the quality of signals recorded with chronically implanted neural electrodes, offering enhanced biocompatibility along with reduced electrode impedance. Combining computational modelling and data from PEDOT:PTS coated and PtIr electrodes in rats, we show that improvements in signal quality with
Karthik Sridhar, Judith Evers, Alexandre Trotier, Manus Biggs, Madeleine M. Lowery   +4 more
wiley   +1 more source

Bio‐Propelled Stomatocyte Nanomotors with Glutathione‐Responsiveness for Osteoarthritis Treatment

Angewandte Chemie, EarlyView.
Glutathione (GSH)‐responsive stomatocyte nanomotors with encapsulated MTX utilize oxygen to achieve autonomous motion and undergo GSH‐induced dissociation, enhancing cellular uptake, tissue penetration, and MTX release within the osteoarthritis (OA) region, thereby improving therapeutic efficacy.
Jianhong Wang, Mengsi Zhan, Hanglong Wu, Maarten Bransen, Ioanna Balmpouzi, Xianwen Lou, Junjie Liu, Nina Wang, Zhiqiang Wang, Heiner Friedrich, Jingxin Shao, Jan C. M. van Hest, Xiangyang Shi   +12 more
wiley   +2 more sources

Using a computationally driven screening to enhance magnetocaloric effect of metal monoborides

JPhys Energy, 2023
In most cases, substitution studies that aim to optimize magnetic properties are performed at the magnetic atomic site. However, in the case of MnB, magnetic substitutions at the Mn site significantly decrease the once promising magnetocaloric and ...
Carlos Romero-Muñiz, Jia Yan Law, Luis M Moreno-Ramírez, Álvaro Díaz-García, Victorino Franco   +4 more
doaj   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Does load position on the trunk affect cardiopulmonary responses of the bearer during simulated front and back infant carrying methods?

Nigerian Journal of Medicine, 2020
Background: The position of the infant on the trunk during back and front infant carrying methods (ICMs) may be a potential factor of maternal physiological changes.
Chidiebele Petronilla Ojukwu, Cyprian Ifeanyi Nnamoko, Adaora Justina Okemuo, Stephen Sunday Ede, Ijeoma Judith Ilo, Chioma Nneka Ikele, Theresa Odunayo Akinola   +6 more
doaj   +1 more source

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

Automated navigation of condensate phase behavior with active machine learning

Nature Communications
Biomolecular condensates are essential cellular structures formed via biomacromolecule phase separation. Synthetic condensates allow for systematic engineering and understanding of condensate formation mechanisms and to serve as cell-mimetic platforms ...
Yannick H. A. Leurs, Willem van den Hout, Andrea Gardin, Joost L. J. van Dongen, Andoni Rodriguez-Abetxuko, Nadia A. Erkamp, Jan C. M. van Hest, Francesca Grisoni, Luc Brunsveld   +8 more
doaj   +1 more source

Neural Activity during Voluntary Movements in Each Body Representation of the Intracortical Microstimulation-Derived Map in the Macaque Motor Cortex. [PDF]

PLoS ONE, 2016
In order to accurately interpret experimental data using the topographic body map identified by conventional intracortical microstimulation (ICMS), it is important to know how neurons in each division of the map respond during voluntary movements.
Noriyuki Higo, Nobuo Kunori, Yumi Murata
doaj   +1 more source

Explaining the lower usage rate of indigenous construction materials in Ghanaian public buildings using bounded rationality

Heliyon, 2023
Judicious use of Indigenous Construction Materials (ICM) contributes to sustainability of a local construction industry. Why has the use of ICMs not contributed to the sustainability of the Ghanaian Construction Industry (GCI), and how can the use of ...
Sarfo Mensah, Samuel Laryea
doaj   +1 more source

A Prototype Toolkit For Evaluating Indoor Environmental Quality In Commercial Buildings [PDF]

, 2013
Measurement of building environmental parameters is often complex, expensive, and not easily proceduralized in a manner that covers all commercial buildings. Evaluating building indoor environmental quality performance is therefore not standard practice.
Anwar, George, Dickerhoff, Darryl, Heinzerling, David, Hoyt, Tyler, Webster, Tom   +4 more
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