Results 31 to 40 of about 13,497 (294)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

ICMS ecológico: análise do ICMS ecológico no estado do Paraná [PDF]

, 2011
TCC (graduação) - Universidade Federal de Santa Catarina, Centro Sócio Econômico, Curso de Ciências Contábeis.O ICMS Ecológico foi criado com a intenção de reduzir perdas de recursos tributários, funciona como uma compensação aos Municípios que possuem ...
Charão, Fernanda Gomes
core  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Análise da constitucionalidade do Protocolo ICMS 21/2011 face ao Sistema Tributário Nacional [PDF]

, 2013
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Jurídicas. Direito.O constituinte determinou que o ICMS, nas operações interestaduais que destinem mercadoria a consumidor final não contribuinte, fosse inteiramente arrecadado ...
Costa, Gabrielle Vilvert da
core  

Protected areas as criteria of Ecological ICMS in Brazilian states

Desenvolvimento e Meio Ambiente, 2020
O ICMS Ecológico é um instrumento econômico que tem sido apontado como uma importante estratégia de associação do incremento do orçamento municipal com a conservação da biodiversidade a partir da criação e manutenção de áreas protegidas.
Isabella Moura Carvalho Lima, Laura Jane Gomes, Milton Marques Fernandes   +2 more
doaj   +1 more source

Oppositely Charged Single Enzyme Nanogels Form Versatile Coacervates for Efficient Enzyme Cascade Catalysis

Advanced Materials, EarlyView.
Oppositely charged single enzyme nanogels (SENs) phase‐separate into bi‐enzymatic coacervate microdroplets, acting as both scaffold and functional units. By tuning SEN ratios, these coacervates create specific microenvironments that enable selective small‐molecule enrichment and efficient intermediate diffusion.
Andoni Rodriguez‐Abetxuko, Nadia A. Erkamp, Neshat Moslehi, Yannick H. A. Leurs, Lars Paffen, Işil Yeşil Gür, Jana Stojanović, Hugo Brasselet, Laura van der Weel, Ulf Hanefeld, Ilja K. Voets, Jan C. M. van Hest   +11 more
wiley   +1 more source

O comportamento do ICMS Ecológico nos municípios do Oeste do Paraná nos anos de 2008, 2009 e 2010 [PDF]

, 2011
TCC (graduação) - Universidade Federal de Santa Catarina, Centro Sócio Econômico, Curso de Ciências Contábeis.Esse trabalho se propõe a verificar o comportamento do ICMS Ecológico nos municípios pertencentes à Associação dos Municípios do Oeste do ...
Carminati, Liana
core  

Neural mechanisms of the temporal response of cortical neurons to intracortical microstimulation

Brain Stimulation
Background: Intracortical microstimulation (ICMS) is used to map neuronal circuitry in the brain and restore lost sensory function, including vision, hearing, and somatosensation.
Karthik Kumaravelu, Warren M. Grill
doaj   +1 more source

Engineering transient dynamics of artificial cells by stochastic distribution of enzymes

Nature Communications, 2021
Here the authors develop a coacervate micromotor that can display autonomous motion as a result of stochastic distribution of propelling units. This stochastic-induced mobility is validated and explained through experiments and theory.
Shidong Song, Alexander F. Mason, Richard A. J. Post, Marco De Corato, Rafael Mestre, N. Amy Yewdall, Shoupeng Cao, Remco W. van der Hofstad, Samuel Sanchez, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest   +10 more
doaj   +1 more source

Multilayered Digital Microfluidic Chip for Cell‐Based Assays

Advanced Materials Interfaces, EarlyView.
A multilayered digital microfluidic (mDMF) chip architecture is introduced to improve throughput and robustness in cell‐based assays. By multilayering electrode components and dielectric layers on glass, this design significantly reduces actuation voltage, maintains reliability, and enables expansion of the operational area with minimum current leakage.
Mert Ozden, Oksana K. Savchak, Burcu Gumuscu   +2 more
wiley   +1 more source