Results 251 to 260 of about 60,513 (316)
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer+8 more
wiley +1 more source
Deciphering cancer therapy resistance via patient-level single-cell transcriptomics with CellResDB. [PDF]
Liu T+5 more
europepmc +1 more source
Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng+10 more
wiley +1 more source
Performance Measurement of Gesture-Based Human-Machine Interfaces Within eXtended Reality Head-Mounted Displays. [PDF]
Angrisani L+6 more
europepmc +1 more source
A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers+10 more
wiley +1 more source
Cost-Effectiveness of Single-Inhaler Versus Multiple-Inhaler Triple Therapy in COPD: A German Healthcare Perspective. [PDF]
Beeh KM+7 more
europepmc +1 more source
Practice makes perfect, especially when doing what we like. [PDF]
Reppa I, McDougall S.
europepmc +1 more source