Results 261 to 270 of about 464,149 (355)

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

From data collection to design principles: A study of smartwatch faces for enhanced information visualization. [PDF]

PLoS One
Dong M, Bian Z, Zhu Y.
europepmc   +1 more source

The Sydney Opera House: politics in the creation of an icon [PDF]

, 2013
Carter, Adrian, Tyrrell, Roger
core  

Functional Integration of Different‐Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis

Advanced Biology, EarlyView.
This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau, Monica A. Rionda, Evelyn Cho, Jamison G. Clark, Robin E. Kruger, Ruth K. Chan‐Sui, Vasantha Padmanabhan, Molly B. Moravek, Ariella Shikanov   +8 more
wiley   +1 more source

Comparing the Level of Pain and Oral Hygiene Status in Patients Receiving Fixed Appliance Therapy Versus Clear Aligner Therapy During the First Phase of Orthodontic Treatment: An In Vivo Study. [PDF]

Cureus
B R, C SB, P MA, K JK, Mearish P, Jacob SM, Haridas A.   +6 more
europepmc   +1 more source

Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development

Advanced Biology, EarlyView.
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng, Wangyu Luo, Yichen Yao, Lichieh Lin, Laiting Chan, Jiarui Lu, Zijing Huang, Jingyi Feng, Le Zhao, Xiaolei Zhang, Liu Yang   +10 more
wiley   +1 more source

Verification of CT/MRI imaging protocol compliance for radiotherapy. [PDF]

J Appl Clin Med Phys
Hu Y, Rijken JD, Arnesen M.
europepmc   +1 more source

Projeto ICON - Integração de CONteúdos: para um novo modelo de descrição

, 2018
Lucília Runa, Francisco Barbedo, Maria José Almeida   +2 more
openalex   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

Noninvasive cardiac output monitoring in septic shock patients: A retrospective study on hemodynamic status and outcomes. [PDF]

Medicine (Baltimore)
Su YJ, Tan ST, Nassef Y.
europepmc   +1 more source