Results 1 to 10 of about 105,264 (200)

ICOS and ICOS ligand: expression patterns and outcomes in oncology patients [PDF]

open access: yesTherapeutic Advances in Medical Oncology
Background: Inducible T-cell co-stimulator (ICOS) and its ligand (ICOSL) form a complex, two-faced immune machinery that can lead to both immune stimulation and inhibition.
Mina Nikanjam   +8 more
doaj   +4 more sources

ICOS regulates the generation and function of human CD4+ Treg in a CTLA-4 dependent manner. [PDF]

open access: yesPLoS ONE, 2013
Inducible co-stimulator (ICOS) is a member of CD28/Cytotoxic T-lymphocyte Antigen-4 (CTLA-4) family and broadly expressed in activated CD4(+) T cells and induced regulatory CD4(+) T cells (CD4(+) iTreg).
Jian Zheng   +8 more
doaj   +5 more sources

Inducible T‐Cell Co‐Stimulator (ICOS) and ICOS Ligand: Dealing With a Two‐Faced Cancer Immunoregulatory System [PDF]

open access: yesCancer Medicine
Background ICOS (inducible T‐cell co‐stimulator) and ICOS ligand (ICOSL) are part of an important, complex pathway that can lead to both immune stimulation and suppression.
Mina Nikanjam   +9 more
doaj   +2 more sources

ICOS Co-Stimulation: Friend or Foe?

open access: yesFrontiers in Immunology, 2016
Over the last 15 years, the inducible T cell co-stimulator (ICOS) has been implicated in a wide variety of immune outcomes, including the induction and regulation of Th1, Th2, and Th17 immunity.
Jason S Stumhofer
exaly   +3 more sources

A view of the European carbon flux landscape through the lens of the ICOS atmospheric observation network [PDF]

open access: yesAtmospheric Chemistry and Physics, 2023
The ICOS (Integrated Carbon Observation System) network of atmospheric measurement stations produces standardized data on greenhouse gas concentrations at 46 stations in 16 different European countries (March 2023).
I. Storm   +6 more
doaj   +1 more source

ICO investors [PDF]

open access: yesFinancial Markets and Portfolio Management, 2019
AbstractWe conduct a detailed analysis of investors in successful initial coin offerings (ICOs). The average ICO has 4700 contributors. The median participant contributes small amounts and many investors sell their tokens before the underlying product is developed.
Rüdiger Fahlenbrach, Marc Frattaroli
openaire   +2 more sources

Levels and clinical significance of follicular helper T cells in peripheral blood of syphilis patients

open access: yesPifu-xingbing zhenliaoxue zazhi, 2023
Objective To investigate the levels of different follicular helper T cells in peripheral blood of syphilis patients and discuss its clinical significance.
Kaixi PAN   +4 more
doaj   +1 more source

Versioning biological cells for trustworthy cell engineering

open access: yesNature Communications, 2022
Full traceability and transparency are important to establish trust in engineered cell lines. Here the authors argue that version control for cell engineering marks a significant step toward more open, reproducible, traceable and ultimately more ...
Jonathan Tellechea-Luzardo   +6 more
doaj   +1 more source

Financial Bubbles for Economic Development: Implications Regarding ICOs

open access: yesStudies in Business and Economics, 2021
Most people consider financial bubbles as the result of speculations and manipulations, and that less of them will make a market economy more efficient. While speculative bubbles no doubt increase the risks and uncertainties of investors, there are many ...
Lorne Frank, Li Tianze
doaj   +1 more source

Ikzf2 Regulates the Development of ICOS+ Th Cells to Mediate Immune Response in the Spleen of S. japonicum-Infected C57BL/6 Mice

open access: yesFrontiers in Immunology, 2021
BackgroundTh cells (helper T cells) have multiple functions in Schistosoma japonicum (S. japonicum) infection. Inducible co-stimulator (ICOS) is induced and expressed in activated T lymphocytes, which enhances the development of B cells and antibody ...
Shihao Xie   +14 more
doaj   +1 more source

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