Results 11 to 20 of about 23,238 (188)

ICOS+ Tregs: A Functional Subset of Tregs in Immune Diseases

Frontiers in Immunology, 2020
Recent studies have reported the pathological effect of ICOS+ T cells, but ICOS signals also widely participate in anti-inflammatory responses, particularly ICOS+ regulatory T (Treg) cells.
Xian-Zhi Xiong
exaly   +3 more sources

ICOS Co-Stimulation: Friend or Foe?

Frontiers in Immunology, 2016
Over the last 15 years, the inducible T cell co-stimulator (ICOS) has been implicated in a wide variety of immune outcomes, including the induction and regulation of Th1, Th2, and Th17 immunity.
Jason S Stumhofer
exaly   +3 more sources

Development and evaluation of the first-in-class nanobody based PET tracer targeting human inducible T-cell co-stimulator receptor [PDF]

EJNMMI Research
Background Inducible T-cell co-stimulator receptor (ICOS) is a conserved biomarker mainly expressed on activated T cells. It had been proved that PET imaging targeting ICOS was a promising strategy for assessment of immune responses in cancer ...
Jianming Li, Shao Duan, Wei You, Yao Zhao, Weiran Li, Zunyu Xiao, Jianyu Liu   +6 more
doaj   +2 more sources

Inducible T-Cell Co-Stimulator (ICOS) and ICOS Ligand: Dealing With a Two-Faced Cancer Immunoregulatory System

Cancer Medicine
Background ICOS (inducible T‐cell co‐stimulator) and ICOS ligand (ICOSL) are part of an important, complex pathway that can lead to both immune stimulation and suppression.
Mina Nikanjam, Hirotaka Miyashita, Aung Naing   +2 more
exaly   +2 more sources

A view of the European carbon flux landscape through the lens of the ICOS atmospheric observation network [PDF]

Atmospheric Chemistry and Physics, 2023
The ICOS (Integrated Carbon Observation System) network of atmospheric measurement stations produces standardized data on greenhouse gas concentrations at 46 stations in 16 different European countries (March 2023).
I. Storm, U. Karstens, C. D'Onofrio, A. Vermeulen, A. Vermeulen, W. Peters, W. Peters   +6 more
doaj   +1 more source

Integrative analysis of T cell subset-specific ICOS expression and tumor HLA class I/II expression in lung adenocarcinoma: implications for their interaction and clinical outcome [PDF]

Cancer Immunology, Immunotherapy
Objectives Inducible T cell costimulator (ICOS) is a CD28-family costimulatory receptor with bidirectional therapeutic effects on antitumor immunity, and HLA-mediated tumor recognition is essential for effective T cell responses.
Hiroyuki Yamada, Rin Yamada, Yoshihiro Komohara, Cheng Pan, Daiki Yoshii, Hiromu Yano, Eri Matsubara, Yusuke Shinchi, Hirotake Tsukamoto, Yukio Fujiwara, Koei Ikeda, Makoto Suzuki   +11 more
doaj   +2 more sources

ICOS+ T helper 2 cells promote the pulmonary fibrosis in systemic sclerosis [PDF]

Molecular Medicine
Background Interstitial lung disease (ILD) is the most frequent complication of systemic sclerosis (SSc), associated with a poor prognosis and limited treatments.
Huimin Zhu, Yuxuan Chen, Yingyi Wu, Yue Zhang, Shanshan Liu, Na You, Mian Liu, Zhikang Wang, Dandan Wang, Lingyun Sun   +9 more
doaj   +2 more sources

Nodal T Follicular Helper Cell Lymphoma With Epstein–Barr Virus‐Positive Neoplastic T Cells Derived From Clonal Hematopoiesis [PDF]

eJHaem, Volume 7, Issue 6, December 2026.
ABSTRACT Introduction Nodal T follicular helper cell lymphoma (nTFHL) with Epstein–Barr virus (EBV)‐positive neoplastic T cells is rare. Methods We report a woman with nTFHL and analyzed EBV‐infected cells using an immunobead‐based method and assessed somatic mutations in lymphoma and lymphoma‐uninvolved bone marrow by targeted sequencing.
Daichi Kishi, Nobuhiro Hiramoto, Daisuke Yamashita, Hayato Maruoka, Yumi Shiroishi, Masashi Nishikubo, Yoshimitsu Shimomura, Ryusuke Yamamoto, Yuya Nagai, Yuka Torii, Hiroshi Kimura, Yasuhito Nannya, Seishi Ogawa, Tadakazu Kondo   +13 more
wiley   +2 more sources

Levels and clinical significance of follicular helper T cells in peripheral blood of syphilis patients

Pifu-xingbing zhenliaoxue zazhi, 2023
Objective To investigate the levels of different follicular helper T cells in peripheral blood of syphilis patients and discuss its clinical significance.
Kaixi PAN, Cong CHEN, Jun ZHANG, Qing LI, Ping LV   +4 more
doaj   +1 more source

Financial Bubbles for Economic Development: Implications Regarding ICOs

Studies in Business and Economics, 2021
Most people consider financial bubbles as the result of speculations and manipulations, and that less of them will make a market economy more efficient. While speculative bubbles no doubt increase the risks and uncertainties of investors, there are many ...
Lorne Frank, Li Tianze
doaj   +1 more source