Results 21 to 30 of about 29,154 (297)
ICOS-related immune responses.
, 2023 The majority of immune-related genes are positively correlated with ICOS expression in TCGA and METABRIC databases, while a small number of genes are negatively associated (A and B).
Jianqiang Shao (12904988) +5 more
core +1 more source
RGIFE: a ranked guided iterative feature elimination heuristic for the identification of biomarkers
BMC Bioinformatics, 2017 Background Current -omics technologies are able to sense the state of a biological sample in a very wide variety of ways. Given the high dimensionality that typically characterises these data, relevant knowledge is often hidden and hard to identify ...
Nicola Lazzarini, Jaume Bacardit
doaj +1 more source
Greenhouse gas observation network design for Africa
Tellus: Series B, Chemical and Physical Meteorology, 2020 An optimal network design was carried out to prioritise the installation or refurbishment of greenhouse gas (GHG) monitoring stations around Africa. The network was optimised to reduce the uncertainty in emissions across three of the most important GHGs:
Alecia Nickless +11 more
doaj +1 more source
The role of ICOS in the development of CD4 T cell help and the reactivation of memory T cells [PDF]
, 2007 We have addressed the role of the inducible costimulator (ICOS) in the development of T cell help for B cells and in the generation, survival and reactivation of memory CD4 T cells and B cells.
MacDonald, Andrew +18 more
core +1 more source
Frontiers in Immunology, 2021 BackgroundTh cells (helper T cells) have multiple functions in Schistosoma japonicum (S. japonicum) infection. Inducible co-stimulator (ICOS) is induced and expressed in activated T lymphocytes, which enhances the development of B cells and antibody ...
Shihao Xie +14 more
doaj +1 more source
Epigenetics, 2020 CTLA-4 blocking therapeutic antibodies are currently under investigation in head and neck squamous cell carcinoma (HNSCC). A better understanding of the epigenetic regulation of the CD28 superfamily members CD28, CTLA-4, and ICOS and their B7 ligands ...
Luka de Vos +9 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2022 Cancer immunotherapy is a powerful tool for inducing antigen-specific antitumor cytotoxic T lymphocytes (CTLs). Next-generation strategies may include vaccination against overexpressed oncogenic tumor-self antigens.
C. Riccay Elizondo +2 more
doaj +1 more source
Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications
OncoImmunology, 2017 The goal of cancer immunotherapy is to establish new or boost pre-existing anticancer immune responses that eradicate malignant cells while generating immunological memory to prevent disease relapse.
Mariona Cabo +5 more
doaj +1 more source
Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing
Molecules, 2023 Emerging advances in the field of in vitro toxicity testing attempt to meet the need for reliable human-based safety assessment in drug development. Intrahepatic cholangiocyte organoids (ICOs) are described as a donor-derived in vitro model for disease ...
Manon C. Bouwmeester +11 more
doaj +1 more source
Journal of Inflammation Research, 2023 Yan Long, Chang-Sheng Xia, Xingyue Zeng, Jinghong Feng, Yinting Ma, Chen Liu Department of Clinical Laboratory, Peking University People’s Hospital, Beijing, People’s Republic of ChinaCorrespondence: Yan Long; Chen Liu, Department of Clinical Laboratory,
Long Y +5 more
doaj