Results 101 to 110 of about 117,111 (323)
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
Advanced Science, EarlyView.An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source
ICOS-deficient and ICOS YF mutant mice fail to control Toxoplasma gondii infection of the brain.
PLoS ONE, 2020 Resistance to chronic Toxoplasma gondii infection requires ongoing recruitment of T cells to the brain. Thus, the factors that promote, sustain, and regulate the T cell response to the parasite in the brain are of great interest.
Carleigh A O'Brien, Tajie H Harris
doaj +1 more source
Advanced Science, EarlyView.Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu +34 more
wiley +1 more source
Advanced Science, EarlyView.T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu +14 more
wiley +1 more source
Blockchain for social good: a quantitative analysis
, 2018 The rise of blockchain technologies has given a boost to social good projects, which are trying to exploit various characteristic features of blockchains: the quick and inexpensive transfer of cryptocurrency, the transparency of transactions, the ability
Bartoletti, Massimo +3 more
core +1 more source
Helsinki Law Review, 2020 ICO on lohkoketjuteknologiaan perustuva rahoituskeino, joka toteutetaan laskemalla liikkeelle lohkoketjuun kytketty instrumentti eli token. Tokeneihin voidaan lohkoketjuteknologian joustavuuden vuoksi kytkeä useita erilaisia ominaisuuksia, kuten osakkeille tyypillisiä ääni- ja omistusoikeuksia tai hyödykkeille tyypillisiä osto- ja käyttöoikeuksia. Tämä
openaire +2 more sources
, 2020 . In situ CO2 and CO measurements from five Integrated Carbon Observation System (ICOS) atmosphere stations have been analysed together with footprint model runs from the regional Stochastic Time-Inverted Lagrangian Transport (STILT) model to develop a ...
I. Levin +12 more
semanticscholar +1 more source
Evaluation and optimization of ICOS atmosphere station data as part of the labeling process
Atmospheric Measurement Techniques, 2020 . The Integrated Carbon Observation System (ICOS) is a pan-European research infrastructure which provides harmonized and high-precision scientific data on the carbon cycle and the greenhouse gas budget. All stations have to undergo a rigorous assessment
C. Yver-Kwok +34 more
semanticscholar +1 more source
Advanced Science, EarlyView.CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang +17 more
wiley +1 more source
Blood Advances, 2020 The treatment of advanced-stage cutaneous T-cell lymphoma (CTCL) remains an unmet medical need. Mogamulizumab, anti-KIR3DL2, and brentuximab vedotin (BV), an anti-CD30 antibody-drug conjugate (ADC) coupled with monomethyl-auristatin-E (MMAE), provided ...
F. Amatore +19 more
semanticscholar +1 more source