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Results 81 to 90 of about 29,154 (297)

Abnormal functional connectivity patterns in temporal lobe epilepsy—An international ENIGMA‐epilepsy study

Epilepsia Open, EarlyView.
Abstract Objectives Temporal lobe epilepsy (TLE) impacts multiple brain networks. Aberrant functional connectivity has been demonstrated in resting‐state networks (RSNs) that mediate higher brain functions in TLE. This study aimed to identify the reproducible patterns of altered functional connectivity in TLE in a large, international cohort through ...
Victoria Ives‐Deliperi +28 more
wiley +1 more source

European Obspack compilation of atmospheric methane data from ICOS and non-ICOS European stations for the period 1984-2024; obspack_ch4_466_GVeu_v10_20240729

This data package contains high accuracy CH4 dry air mole fractions from 69 ICOS and non-ICOS European observatories at in total 148 observation levels, collected by the ICOS Atmosphere Thematic Centre (ATC) and provided by the station contributors.
Stanley, Kieran M, Bergamaschi, Peter, et al. +2 more
core +1 more source

Health System Factors in Head and Neck Cancer Diagnosis: A HEADSpAcE Consortium Qualitative Study in Glasgow and Montevideo

Head &Neck, EarlyView.
ABSTRACT Background Head and neck cancer (HNC) is a devastating diagnosis, with advanced‐stage disease leading to poorer outcomes. This qualitative study aimed to identify health system factors associated with stage of HNC diagnosis. Methods Qualitative semistructured interviews with HNC patients and clinicians were undertaken in two purposively ...
Grant Creaney +196 more
wiley +1 more source

Detection of ICOS⁺T cells by multiplex immunohistochemistry in tumor tissue and its clinical significance in hepatocellular carcinoma

Zhongguo aizheng zazhi, 2019
Background and purpose: Inducible costimulator (ICOS) is a member of B7-CD28 immunoglobulin superfamily and expressed on the surface of activated T cells, which plays an important role in T cell activation and effector functions.
马家强 +4 more
doaj

Inducible T Cell Costimulator Ligand and Inducible T Cell Costimulator Stratification Identify Dichotomous Tumor Microenvironment and Guide Chemo-Immunotherapy in Small Cell Lung Cancer. [PDF]

MedComm (2020)
In small cell lung cancer, high tumor ICOSLG expression drives a microenvironment enriched with immunosuppressive T cells and M2 macrophages. Conversely, ICOSLG low tumors promote CD8+ T cell infiltration. Clinically, high ICOSLG levels predict poor response to immune checkpoint inhibitors and worse survival, whereas low ICOSLG expression indicates ...
Guo Q +9 more
europepmc +2 more sources

Cardiovascular disease incidence and cancer risk in two large European prospective cohorts

International Journal of Cancer, EarlyView.
What's New? Cardiovascular disease (CVD) and cancer share risk factors and biological mechanisms, raising questions about potential associations between the two, particularly regarding CVD duration and cancer onset. Whether CVD influences subsequent cancer risk, however, remains inconclusive.
Emma Fontvieille +25 more
wiley +1 more source

International chronic inflammatory demyelinating polyneuropathy outcome study (ICOS): Protocol of a prospective observational cohort study on clinical and biological predictors of disease course and outcome

, 2019
Chronic inflammatory demyelinating polyneuropathy (CIDP) is a heterogeneous immune-mediated disorder with extensive variation in clinical presentation, electrophysiological phenotype, treatment response and long-term outcome.
ICOS Consortium
core

European Obspack compilation of atmospheric carbon dioxide data from ICOS and non-ICOS European stations for the period 1972-2025; obspack_co2_466_GVeu_v11_20250815

This data package contains high accuracy CO2 dry air mole fractions from 68 ICOS and non-ICOS European observatories at in total 156 observation levels, collected by the ICOS Atmosphere Thematic Centre (ATC) and provided by the station contributors.
Stanley, Kieran M, Bergamaschi, Peter, et al. +2 more
core +1 more source

Analysis of ICOS and ICOS-L expression in NK cells.

, 2019
(A) Left, A representative histogram of ICOS-L expression in splenic WT (black) and ICOS-KO (blue) NK cells. Staining with isotype antibody control depicted in gray.
Umberto Dianzani (84558) +8 more
core +1 more source

Meat Intake and Risk of Gastric and Esophageal Adenocarcinoma in the European Prospective Investigation Into Cancer and Nutrition (EPIC) Study

International Journal of Cancer, EarlyView.
Limited evidence links processed meat intake and non‐cardia gastric cancer, while esophageal adenocarcinoma is increasing in Western countries, where diets are typically high in red and processed meats. Using data from over 450,000 participants from a large prospective study, the authors examined meat consumption and the risk of gastric and esophageal ...
Catalina Bonet +25 more
wiley +1 more source

medicine
prognosis