Results 61 to 70 of about 23,238 (188)
Frontiers in Immunology, 2018 The lethality of blood stage Plasmodium berghei ANKA (PbA) infection is associated with the expression of T-bet and production of cytokine IFN-γ. Expression of inducible costimulator (ICOS) and its downstream signaling has been shown to play a critical ...
Gajendra M. Jogdand +5 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo +10 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Objectives Temporal lobe epilepsy (TLE) impacts multiple brain networks. Aberrant functional connectivity has been demonstrated in resting‐state networks (RSNs) that mediate higher brain functions in TLE. This study aimed to identify the reproducible patterns of altered functional connectivity in TLE in a large, international cohort through ...
Victoria Ives‐Deliperi +28 more
wiley +1 more source
Organoid Coculture Models for Cancer Research and Immunotherapy
Med Research, EarlyView.This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang +9 more
wiley +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.As forests are important for biodiversity and recreation and provide vital resources globally, it is essential that their health can be accurately monitored, for example, by using sap flow probes to measure tree water uptake. We investigated whether sap flow measurements might differ at various locations within the same tree due to variation in wood ...
Stefan Seeger +2 more
wiley +1 more source
Treg‐stromal cell axis in tissue repair and autoimmune diseases: Mechanisms and clinical translation
Rheumatology &Autoimmunity, EarlyView.The Treg‐stromal cell axis as a central regulator of tissue repair and immune tolerance. Under physiological conditions, bidirectional communication between Tregs and stromal cells—mediated by cell‐surface molecular contacts, anti‐inflammatory cytokines, and extracellular vesicles—orchestrates inflammation resolution, immune tolerance, and complete ...
Peiyan Zhang +2 more
wiley +1 more source
Sustainable Production Planning: Insights Into Factors, Models, and Solution Methods
Sustainable Development, EarlyView.ABSTRACT Effective resource management remains a major challenge for organizations seeking to balance economic efficiency with environmental and social responsibility. In this context, production planning becomes a strategic mechanism for integrating sustainability into industrial operations.
Daysi Ortiz +2 more
wiley +1 more source
Ontogeny of foraging behaviour in an opportunistic gull inhabiting urban marine ecosystems
Wildlife Biology, EarlyView.Urbanization affects ecosystems by reducing biodiversity and displacing species from native habitats. While some suffer, others, like urban wildlife, adapt through innovative feeding and behaviours that improve their fitness in human‐altered settings. Despite research on wildlife in urban areas, the development of foraging behaviour in urban species is
Joan Navarro +7 more
wiley +1 more source
Government by WhatsApp? Transparency, Secrecy and Avoidance during Covid in the UK
The Political Quarterly, EarlyView.Abstract It has been claimed repeatedly that transparency undermines decision‐making. The fear of disclosure means officials and politicians may not discuss policy fully, are inhibited from giving frank advice, and could avoid proper record keeping. The use of informal communications—particularly the use of WhatsApp—makes all these tensions more likely,
Ben Worthy, Martin Rosenbaum
wiley +1 more source
Zhongguo aizheng zazhi, 2019 Background and purpose: Inducible costimulator (ICOS) is a member of B7-CD28 immunoglobulin superfamily and expressed on the surface of activated T cells, which plays an important role in T cell activation and effector functions.
马家强 +4 more
doaj