Results 51 to 60 of about 117,111 (323)
A mutation in caspase-9 decreases the expression of BAFFR and ICOS in patients with immunodeficiency and lymphoproliferation [PDF]
, 2015 Lymphocyte apoptosis is mainly induced by either death receptor-dependent activation of caspase-8 or mitochondria-dependent activation of caspase-9. Mutations in caspase-8 lead to autoimmunity/lymphoproliferation and immunodeficiency. This work describes
Boggio, E +15 more
core +2 more sources
Journal of Business Venturing Insights, 2020 Initial coin offerings (ICOs) represent an innovative and new funding mechanism for new technology ventures. In our comprehensive review of the industry’s evolution, we show that despite its short history, there have been dramatic changes and shifts in ...
C. Bellavitis +2 more
semanticscholar +1 more source
Transcriptome profile and clinical characterization of ICOS expression in gliomas
Frontiers in Oncology, 2022 Inducible co-stimulator (ICOS), an immune costimulatory molecule, has been found to play an essential role across various malignancies. This study investigated the transcriptome profile and clinical characterization of ICOS in gliomas.
Jin Wang, Fei Shi, Aijun Shan
doaj +1 more source
Intercomparison of soil pore water extraction methods for stable isotope analysis [PDF]
, 2016 Funded by NSERC Discovery Grant U.S. Forest Service U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy, Bioenergy Technologies OfficePeer ...
McDonnell, Jeffery J. +2 more
core +1 more source
Smoking affects gene expression in blood of patients with ischemic stroke. [PDF]
, 2019 ObjectiveThough cigarette smoking (CS) is a well-known risk factor for ischemic stroke (IS), there is no data on how CS affects the blood transcriptome in IS patients.MethodsWe recruited IS-current smokers (IS-SM), IS-never smokers (IS-NSM), control ...
Ander, Bradley P +6 more
core +2 more sources
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity
Cellular & Molecular Immunology, 2021 T follicular helper (Tfh) cells are crucial for regulating autoimmune inflammation and protective immunity against viral infection. However, the molecular mechanism controlling Tfh cell differentiation is poorly understood.
Xin-fang Huang +13 more
semanticscholar +1 more source
Determinants of ICO success and post-ICO performance
Borsa Istanbul Review, 2023 Initial coin offerings (ICOs) have emerged as an alternative way of raising funds for entrepreneurial ventures to develop a new project or product. In this study, a comprehensive analysis is conducted on the determinants of ICO success and aftermarket performance of ICOs.
Aylin Aslan +2 more
openaire +4 more sources
ICOS Is an Indicator of T-cell–Mediated Response to Cancer Immunotherapy
Cancer Research, 2020 ICOS ImmunoPET is a promising strategy to noninvasively predict and monitor immunotherapy response. Immunotherapy is innovating clinical cancer management. Nevertheless, only a small fraction of patient's benefit from current immunotherapies.
Zunyu Xiao +3 more
semanticscholar +1 more source
Nanomaterials, 2021 Osteoporotic bone fractures represent a critical clinical issue and require personalized and specific treatments in order to stimulate compromised bone tissue regeneration.
S. Fiorilli +9 more
semanticscholar +1 more source
B7h triggering inhibits the migration of tumor cell lines [PDF]
, 2014 Vascular endothelial cells (ECs) and several cancer cells express B7h, which is the ligand of the ICOS T cell costimulatory molecule. We have previously shown that B7h triggering via a soluble form of ICOS (ICOS-Fc) inhibits the adhesion of ...
Baldanzi, Gianluca +17 more
core +1 more source