Results 91 to 100 of about 10,936,957 (328)
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Idea generation (IG) is critical for innovation and maintaining a competitive edge in today's fast-paced global market, where generating novel and valuable ideas is fundamental to a firm’s innovative capabilities and its long-term success.
Mc Caslin, Linda
core +3 more sources
Idea generation support system using recollection of visual representation
Nihon Kikai Gakkai ronbunshu, 2016 Recently, variety of products and services has become diverse, and it is getting more difficult to produce innovative product which matches user needs.
Tomoyuki KOYANAGI, Kazutaka UEDA
doaj +1 more source
Having a creative day: understanding entrepreneurs’ daily idea generation through a recovery lens
, 2018 Prior research has shown that trait creativity is important for becoming an entrepreneur and successful in business. We explore a new perspective by investigating how recovery from work stress influences entrepreneurs' daily idea generation, a key aspect
E. Weinberger +3 more
semanticscholar +1 more source
NeuroImage, 2019 The neuroscientific investigation of creative cognition has advanced by considering the functional connectivity between brain regions and its dynamic changes over time, which are consistent with stages in the ideation process.
C. Rominger +8 more
semanticscholar +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Data Science as an Innovation Challenge: From Big Data to Value Proposition
Technology Innovation Management Review, 2018 Analyzing “big data” holds huge potential for generating business value. The ongoing advancement of tools and technology over recent years has created a new ecosystem full of opportunities for data-driven innovation.
Victoria Kayser +2 more
doaj
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Модернизация, инновация, развитие, 2015 Many companies see innovation as key to their success and are using idea crowdsourcing to help their companies innovate. However, it is often difficult to motivate individuals to think practically and from management’s perspective, and to measure ...
David Powell
doaj
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source