Results 81 to 90 of about 362,466 (258)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Un-Meetings as tools for translational idea generation: A semantic content analysis of an Opioid Crisis Un-Meeting. [PDF]

open access: yesJ Clin Transl Sci, 2022
Yousefi Nooraie R   +5 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Attitude and Entrepreneurial Intention Among Rural Community: the Mediating Role of Entrepreneurial Opportunity Recognition

open access: yesSHS Web of Conferences, 2015
Entrepreneurship has been well documented to have an economic and social implication for the nation to increase income. Most of developing countries give further consideration to include entrepreneurship as an agenda to help the poor to increase the ...
Dahalan Norziani   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reimagining Learning Spaces of the Future: An Interprofessional, Virtual Workshop Utilizing Rapid Idea Generation and Lean Startup Methodologies. [PDF]

open access: yesMedEdPORTAL, 2022
Billings H   +12 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Noninvasive brain stimulation to lateral prefrontal cortex alters the novelty of creative idea generation. [PDF]

open access: yesCogn Affect Behav Neurosci, 2021
Kenett YN   +3 more
europepmc   +1 more source

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