Results 101 to 110 of about 5,558,675 (362)

Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]

, 2017
Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K, Minami, Itsunari, Nakano, Atsushi, Nakano, Haruko, Nakatsuji, Norio, Scharnhorst, Kelsey S, Stieg, Adam Z, Zhu, Huanqi   +7 more
core   +2 more sources

Identification of Birds through DNA Barcodes

PLoS Biology, 2004
Short DNA sequences from a standardized region of the genome provide a DNA barcode for identifying species. Compiling a public library of DNA barcodes linked to named specimens could provide a new master key for identifying species, one whose power will ...
P. Hebert, M. Stoeckle, Tyler S. Zemlak, C. Francis   +3 more
semanticscholar   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Global parameter identification of stochastic reaction networks from single trajectories [PDF]

, 2011
We consider the problem of inferring the unknown parameters of a stochastic biochemical network model from a single measured time-course of the concentration of some of the involved species.
A Auger, AL Barabási, B Munsky, C Andrieu, CL Müller, DT Gillespie, DT Gillespie, E Cinquemani, ET Jaynes, G Kjellström, G Kjellström, G Kjellström, G Stock, H Kitano, H Kitano, H Koeppl, H Qian, JA Helmuth, JK Pritchard, JR Lakowicz, K Koutroumpas, L Ljung, M Hafner, O Mason, O Wolkenhauer, P Marjoram, R Albert, R Grima, R Ramaswamy, R Ramaswamy, R Ramaswamy, R Ramaswamy, R Ramaswamy, RJ Boys, S Reinker, SH Strogatz, SK Poovathingal, T Toni, TG Kurtz   +38 more
core   +1 more source

Identification of a Unique TGF-β Dependent Molecular and Functional Signature in Microglia

Nature Neuroscience, 2013
Microglia are myeloid cells of the CNS that participate both in normal CNS function and in disease. We investigated the molecular signature of microglia and identified 239 genes and 8 microRNAs that were uniquely or highly expressed in microglia versus ...
O. Butovsky, Mark P. Jedrychowski, C. Moore, R. Cialic, Amanda J Lanser, Galina Gabriely, T. Koeglsperger, Ben Dake, Pauline M. Wu, Camille E. Doykan, Zain Fanek, Liping Liu, Zhuoxun Chen, J. Rothstein, R. Ransohoff, S. Gygi, J. Antel, H. Weiner   +17 more
semanticscholar   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Data reliability in complex directed networks [PDF]

, 2013
The availability of data from many different sources and fields of science has made it possible to map out an increasing number of networks of contacts and interactions. However, quantifying how reliable these data are remains an open problem.
Cozzo, Emanuele, Moreno, Yamir, Sanz, Joaquín   +2 more
core   +2 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Error Graphs and the Reconstruction of Elements in Groups [PDF]

, 2009
Packing and covering problems for metric spaces, and graphs in particular, are of essential interest in combinatorics and coding theory. They are formulated in terms of metric balls of vertices.
Levenshtein, Vladimir, Siemons, Johannes
core   +2 more sources

Assessment of BOLD and GenBank – Their accuracy and reliability for the identification of biological materials

PLoS ONE, 2019
Taxonomic identification of biological materials can be achieved through DNA barcoding, where an unknown “barcode” sequence is compared to a reference database.
K. Meiklejohn, Natalie Damaso, J. Robertson   +2 more
semanticscholar   +1 more source