Results 91 to 100 of about 1,001,404 (308)

Risk assessment for hydrophobic disinfectants and antiseptics as contaminants in freshwater using risk quotient and network pharmacology approaches

open access: yesiScience
Summary: Increasing public use of disinfectants and antiseptics (DAs) has raised concerns about their environmental contamination and adverse effects on non-target organisms, despite critical knowledge gaps in the ecological risks posed by DAs.
Songyi Wei   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Physical strength, body composition, and G-test results of air force cadets based on nutrition knowledge differences

open access: yesScientific Reports
The Gravitational Acceleration Test (G-test) is a demanding, and sophisticated high-intensity physical activity, greatly influenced by individual body composition and physical strength.
Jun-Young Sung, Kyu-Lim Lee
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

RALSTONIA SOLANACEARUM: FEATURES OF BIOLOGY AND IDENTIFICATION

open access: yesMicrobiology&Biotechnology, 2012
Ralstonia solanacearum – a causative agent of bacterial wilt for a wide range of plants, with a significant area of geographic distribution. Having South American origin, the agent has demonstrated the phenomenal adaptive properties during the second half of the 20th century, spreading and adapted to the conditions of all continents except the polar ...
openaire   +5 more sources

Exosome-mediated Advancements in Plastic Surgery: Navigating Therapeutic Potential in Skin Rejuvenation and Wound Healing

open access: yesPlastic and Reconstructive Surgery, Global Open
Summary:. Exosomes, tiny extracellular vesicles derived from various cells such as adipose-derived stem cells, bone marrow-derived mesenchymal stem cells, and human umbilical cord mesenchymal stem cells, exhibit considerable potential in wound healing ...
Soo Yeon Park, MD, Kyu-Ho Yi, MD, PhD
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Integrating motion capture technology and intraoral ultrasonography for 3D anatomical analysis

open access: yesScientific Reports
The inherent two-dimensional (2D) nature of ultrasonography (US) limits its accuracy in visualizing complex intraoral structures. This proof-of-concept feasibility study introduces a novel approach integrating motion-capture technology and three ...
Soo-Bin Kim   +5 more
doaj   +1 more source

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