Isocitrate Dehydrogenase-Mutant Astrocytomas: Risk Stratification and Therapeutic Advance. [PDF]
Wei S, Xu X, Bao J, Pan Z.
europepmc +1 more source
The polymorphic behaviour of the three forms of artemisinin was investigated using single‐crystal X‐ray diffraction in a diamond anvil cell, with notable observation of a pressure‐induced phase transition from form (II) to form (III).Artemisinin (ART) is mainly used for the treatment of malaria and exhibits polymorphism with two known crystalline forms.
Banaz Fetah +4 more
wiley +1 more source
Radiomics-based models to predict IDH mutation status and prognosis in gliomas using MRI: a multicenter study. [PDF]
Sümer-Arpak E +6 more
europepmc +1 more source
NADPH dehydrogenase gene deletion significantly triggered NADPH/NADP+ increase in mutant strains. NADPH gene deletion promoted Fatty acid biosynthesis and repressed β‐oxidation. NADPH gene deletion decreased oxidative phosphorylation and increased substrate‐level phosphorylation. Mutants exhibited hypersensitivity to oxidative stress, but promoted more
Yanling Qiu +6 more
wiley +1 more source
From Epigenetic Constraint to Evolutionary Escape: Cell-State Transitions and Selective Pressures During Malignant Transformation in Lower-Grade Gliomas. [PDF]
Wu H, Wei Y, Zhang XD, Qi L.
europepmc +1 more source
Corrigendum to: Contralateral neurofluid dynamics predict survival in IDH wild-type glioblastoma: A DTI-ALPS and free water imaging study. [PDF]
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Primitive neuronal component is a frequent finding among IDH-mutant astrocytomas with RB1 alterations. [PDF]
Slocum CC +12 more
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ABSTRACT Cholangiocarcinoma (CCA) remains a difficult‐to‐treat biliary malignancy in which therapeutic stratification increasingly depends on predictive biomarkers. Although next‐generation sequencing is essential for the detection of targetable genomic alterations, immunohistochemistry (IHC) retains a practical role because it is widely available ...
Francesco Vasuri +3 more
wiley +1 more source
Beyond Tumor Volume: An Integrated Radiological Model of Tumor Load, Anatomical Spread, and Mass Effect for Survival Prediction in Adult Grade 4 Diffuse Astrocytic Tumors. [PDF]
Sarac ME +9 more
europepmc +1 more source

