Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics
MedComm – Oncology, Volume 5, Issue 2, June 2026.Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang +7 more
wiley +1 more source
Percutaneous endoscopic discectomy and dural repair for L3-L4 intradural lumbar disc herniation presenting with cauda equina syndrome: A case report with a literature review. [PDF]
Orthop Rev (Pavia)Maheshati A +5 more
europepmc +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
MedComm – Oncology, Volume 5, Issue 2, June 2026.Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
Amide proton transfer and arterial spin labeling for non-invasive molecular stratification of glioma: a multi-dataset imaging biomarker study. [PDF]
NeuroradiologyEssed R +7 more
europepmc +1 more source
Theranostic Advancements in Brain Cancer: Promising Approaches for Emerging Therapy
MedComm – Oncology, Volume 5, Issue 2, June 2026.Strategies for improving intra‐arterial administration (A) and photodynamic therapy in brain cancer (B). Improving intra‐arterial (IA) administration and photodynamic therapy (PDT) for brain cancer involves enhancing tumor targeting and breaching the blood–brain barrier (BBB). Key strategies include super selective catheterization, using osmotic agents
Bipraban Khanra, Manoj Kumar Sarangi
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Boron‐10 carriers and their applications in boron neutron capture therapy
Precision Radiation Oncology, Volume 10, Issue 2, Page 205-241, June 2026.Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang +7 more
wiley +1 more source
Comparison of Fluorescent Probes for IDH-Wildtype Glioblastoma, Metastatic Brain Tumors, and PCNSL: A Biomechanical Perspective. [PDF]
Int J Mol SciZheng Z, Kobayashi A, Kitagawa Y.
europepmc +1 more source
Public Health Challenges, Volume 5, Issue 2, June 2026.Double burden of malnutrition at household level (DBMHL) is a new challenging public health concern in South Asian countries, defined by the coexistence of overweight mothers and undernourished children. With 208,822 respondents’ information, the decomposition analysis revealed that DBMHL was more prevalent in the wealthiest families, and elective ...
Maliha Mahazabin +2 more
wiley +1 more source