Results 61 to 70 of about 154,739 (326)

Reinforcements and augmentations with the long head of the biceps tendon in shoulder surgery: a narrative review

EFORT Open Reviews
The long head of the biceps tendon (LHBT) has recently emerged as a therapeutic option for various shoulder pathologies. Synthetic materials and allografts have not shown sufficient resistance or favorable outcomes to restore rotator cuff native tissue ...
Alberto Guevara-Alvarez, Edwin Valencia-Ramón, Alejandro Lopez-Villers, Luis Fernando Navarro-Pérez, Israel Gonzalez-Rizo, Gonzalo Eduardo Gomez, Alexandre Laedermann   +6 more
doaj   +1 more source

Non-Geometric Fluxes, Quasi-Hopf Twist Deformations and Nonassociative Quantum Mechanics [PDF]

, 2014
We analyse the symmetries underlying nonassociative deformations of geometry in non-geometric R-flux compactifications which arise via T-duality from closed strings with constant geometric fluxes. Starting from the non-abelian Lie algebra of translations
Alekseevsky D., Beggs E., Dionysios Mylonas, Drinfeld V. G., Peter Schupp, Richard J. Szabo   +5 more
core   +3 more sources

An independently validated nomogram for isocitrate dehydrogenase-wild-type glioblastoma patient survival. [PDF]

, 2019
BackgroundIn 2016, the World Health Organization reclassified the definition of glioblastoma (GBM), dividing these tumors into isocitrate dehydrogenase (IDH)-wild-type and IDH-mutant GBM, where the vast majority of GBMs are IDH-wild-type.
Barnholtz-Sloan, Jill S, Berger, Mitchel S, Chunduru, Pranathi, Cioffi, Gino, Gittleman, Haley, Molinaro, Annette M, Sloan, Andrew E   +6 more
core   +1 more source

Targeting Isocitrate Dehydrogenase (IDH) in Solid Tumors: Current Evidence and Future Perspectives

Cancers
Simple Summary Isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) are essential metabolic enzymes involved in the tricarboxylic acid (TCA) cycle.
Francesca Carosi, E. Broseghini, L. Fabbri, Giacomo Corradi, Riccardo Gili, Valentina Forte, R. Roncarati, Daria Maria Filippini, Manuela Ferracin   +8 more
semanticscholar   +1 more source

Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas.

Neuro-Oncology, 2021
BACKGROUND Chemotherapy improves overall survival after surgery and radiotherapy for newly diagnosed high-risk IDH-mutant low-grade gliomas, but a proportion of patients treated with temozolomide (TMZ) will develop recurrent tumors with TMZ-induced ...
Yao Yu, J. Villanueva-Meyer, M. Grimmer, S. Hilz, D. Solomon, Serah Choi, M. Wahl, T. Mazor, C. Hong, Anny Shai, J. Phillips, B. Wainer, M. McDermott, D. Haas-Kogan, Jennie W. Taylor, N. Butowski, Jennifer L. Clarke, M. Berger, A. Molinaro, Susan M. Chang, J. Costello, N. Oberheim Bush   +21 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Alonso, Jimena, Fabiana Larrobla y Mariana Risso. Avanzar a tientas: cronología de las luchas por verdad y justicia: 1985 - 2015. Uruguay: Mastergraf, 2016

Historia y Memoria, 2019
Reseña crítica del libro Avanzar a tientas: cronología de las luchas por verdad y justicia: 1985 - 2015 de Jimena Alonso, Fabiana Larrobla y Mariana Risso.
Paula Zubillaga
doaj   +1 more source

Treatment of IDH-mutant glioma in the INDIGO era

npj Precision Oncology
Gliomas are the most common primary brain tumor and are uniformly lethal. Despite significant advancements in understanding the genetic landscape of gliomas, standard-of-care has remained largely unchanged.
Mathew Lin, A. Tsai, Kalil G. Abdullah, S. McBrayer, Diana D. Shi   +4 more
semanticscholar   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick, Cheick O. Soumah, Malé Doré, Oumar Mara, Desiré Neldje, Fodé A. Cissé, Toure M. Lamine, Aminata Diallo, Seungwon Lee, Siddharth Satish, Alexander J. X. Chen, Alice Liu, Nomin Enkhtsetseg, Farrah J. Mateen, The Guinea Epilepsy Project   +14 more
wiley   +1 more source

El suicidio como problema gubernamental en la ciudad de Córdoba, Argentina

Revista Ñanduty, 2019
En este trabajo me propongo indagar respecto de la producción social del suicidio como problema gubernamental en la ciudad de Córdoba/Argentina de los últimos años.
Santiago Manuel Romero
doaj   +1 more source