Results 111 to 120 of about 47,637 (238)

Plexogenic pulmonary hypertension associated with POEMS syndrome

Respiratory Medicine Case Reports, 2017
Pulmonary hypertension is one of the well-known clinical manifestations of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome, occurring in approximately 25–30% of the affected individuals. However, the
Thomas Czeczok, Peter Lin, Eunhee Yi
doaj   +1 more source

Role of curcumin in idiopathic pulmonary arterial hypertension treatment: A new therapeutic possibility [PDF]

, 2013
The idiopathic pulmonary arterial hypertension is a complex disease that mainly affects pulmonary arterial circulation. This undergoes a remodeling with subsequent reduction of flow in the small pulmonary arteries.
BRONTE, Enrico, Coppola, G, DI MICELI, Riccardo, NOVO, Salvatore, RUSSO, Antonio, SUCATO, Vincenzo   +5 more
core   +1 more source

Sustained Idiopathic Outflow Tract Ventricular Tachycardia: Clinical Evidence for RVOT Predominance

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Idiopathic outflow tract premature ventricular contractions (PVCs) are most commonly localized in the right ventricular outflow tract (RVOT). The clinical significance of sustained outflow tract ventricular tachycardia (OT‐VT) regarding any predominance to one specific anatomic area remains uncertain.
Moneeb Khalaph, Nadica Trajkovska, Maxim Didenko, Mustapha El Hamriti, Guram Imnadze, Denise Guckel, Philipp Lucas, Martin Braun, Thomas Fink, Vanessa Sciacca, Ersan Akkaya, Sebastian E. Beyer, Hassan El‐Shirbiny, Maximilian Mörsdorf, Christian Sohns, Philipp Sommer, Angeliki Darma   +16 more
wiley   +1 more source

Refractory cardiac arrest during epidural anesthesia for caesarean section in a patient with supra-systemic pulmonary hypertension rescued by VA ECMO

Saudi Journal of Anaesthesia
Patients with severe pulmonary arterial hypertension (PAH) tolerate the hemodynamic changes of pregnancy poorly and should be referred early to an experienced expert multidisciplinary team (MDT) in a tertiary care center early in pregnancy.
Nisar A. Soomro, Raed S. Altowairki, Riaz N. Ahmed, Wesam I. Kurdi   +3 more
doaj   +1 more source

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension. [PDF]

, 2018
Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension ...
Ayon, Ramon J, Balistrieri, Angela, Black, Stephen M, Chen, Jiwang, Desai, Ankit A, Garcia, Joe GN, Gu, Yali, Makino, Ayako, Rischard, Franz, Song, Shanshan, Tang, Haiyang, Vanderpool, Rebecca, Vinjamuri, Sujana, Wang, Jian, Wang, Ziyi, Wu, Kang, Yuan, Jason X-J, Zhang, Qian, Zhou, Guofei   +18 more
core   +1 more source

Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Study overview: simultaneous right heart catheterization, gut microbiome analysis, and plasma blood metabolomics in a cohort of prevalent pulmonary arterial hypertension patients. Key findings: gut microbial Lactobacillus species associated with altered gut‐derived metabolite levels, superior measures of right ventricular structure and function, and ...
Arun Jose, Senu Apewokin, Nicholas J. Ollberding, Qing Duan, Jennifer Trannguyen, Sasha Z. Prisco, Thenappan Thenappan, Anna R. Hemnes, Jean M. Elwing   +8 more
wiley   +1 more source

Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. [PDF]

, 2020
Altered metabolism in pulmonary artery smooth muscle cells (PASMCs) and endothelial cells (PAECs) contributes to the pathology of pulmonary hypertension (PH), but changes in substrate uptake and how substrates are utilized have not been fully ...
D' Alessandro, Angelo, Freeman, Scott, Graham, Brian B, Gu, Sue, Hernandez-Saavedra, Daniel, Kassa, Biruk, Kumar, Rahul, Lee, Michael H, Mickael, Claudia, Reisz, Julie A, Sanders, Linda, Stenmark, Kurt R, Tuder, Rubin M   +12 more
core   +1 more source

Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects. [PDF]

, 2015
Pulmonary arterial hypertension (PAH) is an often fatal disorder resulting from several causes including heterogeneous genetic defects. While mutations in the bone morphogenetic protein receptor type II (BMPR2) gene are the single most common causal ...
Abdalla, Adzhubei, Aldred, Aldred, Archer, Austin, Austin, Austin, Badesch, Best, Best, Chaouat, Chen, Chida, Chida, Chidlow, Choi, Cogan, Cogan, Dahal, David, Deng, Donnelly, Drab, Drake, Elliott, Eyries, Eyries, Feng, Foletta, Frydman, Fujiwara, Germain, Girerd, Girerd, Girerd, Greenwald, Harrison, Harrison, Hinderhofer, Hong, Huang, Humbert, Ishiwata, Jones, Kabata, Koehler, Kumar, Lane, Larkin, Liu, Liu, Long, Ma, Machado, Machado, Machado, Machado, Mache, Mair, Maniatis, McLaughlin, Mercier, Minshall, Murata, Möller, Nasim, Nasim, Nishihara, Nohe, Pfarr, Pfarr, Ranchoux, Remillard, Rigueur, Rosenzweig, Rudarakanchana, Ryan, Shi, Shintani, Simonneau, Smoot, Sobolewski, Soubrier, Sztrymf, Tenorio, Thomson, Trembath, Tuder, Vonk-Noordegraaf, Wang, Wang, Wang, West, West, West, Xu, Young, Yuan, Zhao, Zhao   +100 more
core   +2 more sources

Mitochondrial reprogramming in lung cancer: a therapeutic vulnerability and a strategy for reversing drug resistance

The Journal of Pathology, Volume 269, Issue 2, Page 149-163, June 2026.
Abstract The conceptualization of mitochondria, previously restricted to their function as cellular ‘powerhouses’, has evolved to recognize their function as central coordinating hubs for the orchestration of cancer cell metabolism, signaling, and fate determination.
Woo Hyun Park
wiley   +1 more source

Coexistence of pulmonary arterial hypertension and straight back syndrome in a patient with a novel BMPR2 variant affecting cytoplasmic tail domain

European Journal of Medical Research
Background Pathologic variants in the bone morphogenetic protein receptor-2 (BMPR2) gene cause a pulmonary arterial hypertension phenotype in an autosomal-dominant pattern with incomplete penetrance.
Mi Tang, Jun Luo, Qingqing Liu, Jie Song
doaj   +1 more source