Results 141 to 150 of about 204,699 (375)

Four decades of heart–lung transplantation: Milestones and outcomes in advanced cardiorespiratory failure

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Heart–lung transplantation (HLTx) remains a life‐saving intervention for patients with end‐stage cardiopulmonary failure. We retrospectively analysed long‐term HLTx outcomes at our centre to assess survival trends and evaluate the impact of evolving immunosuppressive, surgical and perioperative strategies.
L. Lily Rosenthal   +10 more
wiley   +1 more source

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis [PDF]

open access: yes, 2012
Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies and characterized by excessive collagen deposition and subsequent fibrosis.
Anderson, G.P.   +19 more
core   +2 more sources

Circulating oxylipins predict mortality in heart failure with preserved ejection fraction

open access: yesESC Heart Failure, EarlyView.
A targeted LC–MS lipidomics approach identified arterial 15‐keto PGF2a as associated with 5‐year mortality in 90 patients with HFpEF. Abstract Aims Heart failure with preserved ejection fraction (HFpEF) poses significant diagnostic, prognostic and therapeutic challenges, with high morbidity and mortality rates.
Vaishnavi Aradhyula   +12 more
wiley   +1 more source

Role of NPPB for recovery post ventricular assist device in paediatric dilated cardiomyopathy: Single‐cell multiomics

open access: yesESC Heart Failure, EarlyView.
This study investigated factors associated with left ventricular recovery after LVAD implantation in paediatric dilated cardiomyopathy. Patients were classified into recovery and non‐recovery groups. Single‐nucleus sequencing revealed higher NPPB expression and altered apoptosis‐related pathways in the recovery group.
Yosuke Kugo   +7 more
wiley   +1 more source

Prediction of progression in idiopathic pulmonary fibrosis using CT scans atbaseline: A quantum particle swarm optimization - Random forest approach [PDF]

open access: yes, 2019
Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease characterized by an unpredictable progressive declinein lung function. Natural history of IPF is unknown and the prediction of disease progression at the time ofdiagnosis is notoriously ...
Brown, Matthew S.   +4 more
core  

Update on diagnosis and treatment of idiopathic pulmonary fibrosis

open access: yesJornal Brasileiro de Pneumologia, 2015
Idiopathic pulmonary fibrosis is a type of chronic fibrosing interstitial pneumonia, of unknown etiology, which is associated with a progressive decrease in pulmonary function and with high mortality rates. Interest in and knowledge of this disorder have
José Baddini-Martinez   +5 more
doaj   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

open access: yesIbrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo   +7 more
wiley   +1 more source

Rapidly Progressive Pulmonary Fibrosis in a Patient Treated with Danazol for Idiopathic Thrombocytopenic Purpura

open access: yesCanadian Respiratory Journal, 2004
The case of a patient that developed pulmonary fibrosis two months after initiation of danazol for treatment of idiopathic thrombocytopenic purpura is described.
Smita Pakhale   +3 more
doaj   +1 more source

Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis

open access: yesScience Translational Medicine, 2019
Interleukin-11 is important for lung fibroblast activation in idiopathic pulmonary fibrosis, and its signaling represents a therapeutic target. Targeting IL-11 in lung fibrosis In idiopathic pulmonary fibrosis (IPF), chronic activation of invasive ...
B. Ng   +21 more
semanticscholar   +1 more source

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