Results 151 to 160 of about 106,594 (302)

Characterising Patient Pathways Prior to the Diagnosis of Interstitial Lung Disease

Respirology, EarlyView.
ABSTRACT Background and Objective Interstitial lung diseases (ILDs) lead to breathlessness, cough, deteriorating quality of life and early death. Patients are typically diagnosed late in their disease course when existing lung damage cannot be reversed.
Caitlin C. Fermoyle, John Townend, Vidya Navaratnam, Nicole Goh, Francesca Gonnelli, Neva Eleangovan, Ursie Smith, Heath Heatley, Victoria Carter, David B. Price, Richard Hubbard, Tamera J. Corte   +11 more
wiley   +1 more source

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, EarlyView.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source

Blocking endothelin: breaking new ground

European Respiratory Review, 2007
Endothelin is one of a number of profibrotic cytokines and growth factors, along with transforming growth factor-beta, connective tissue growth factor and tumour necrosis factor-alpha, thought to be involved in the pathogenesis of idiopathic pulmonary ...
R. M. du Bois
doaj  

Evaluation of progressive pulmonary fibrosis in non-idiopathic pulmonary fibrosis-interstitial lung diseases: a cross-sectional study

BMC Pulmonary Medicine
Background Progressive pulmonary fibrosis is the symptomatic, physiological, and radiological progression of interstitial lung diseases. The aim of this study was to examine the relationship between progressive pulmonary fibrosis and demographic ...
Özlem Erçen Diken, Ömür Güngör, Hüseyin Akkaya   +2 more
doaj   +1 more source

Inhaled beclomethasone/formoterol in idiopathic pulmonary fibrosis: A randomised controlled exploratory study [PDF]

, 2017
Brindle, Kayleigh, Crooks, Michael G., Fraser, Simon D., Hart, Simon P., Morice, Alyn H., Wright, Caroline E.   +5 more
core   +2 more sources

Deep‐Learning Algorithm Diagnostic Support for Usual Interstitial Pneumonia Pattern Recognition in Fibrotic Interstitial Lung Disease

Respirology, EarlyView.
ABSTRACT Background and Objective High resolution computed tomography (HRCT) scan diagnostic classification for usual interstitial pneumonia (UIP) plays a critical role in therapeutic decision‐making and clinical trial eligibility for interstitial lung disease (ILD) patients, but is subject to variability.
Caitlin C. Fermoyle, John A. Mackintosh, Vidya Navaratnam, Samantha J. Ellis, Wendy A. Cooper, Nicole S. L. Goh, Yuben Moodley, Paul N. Reynolds, Christopher J. Zappala, Peter Hopkins, Ian N. Glaspole, Tamera J. Corte, Simon L. F. Walsh, on behalf of the SOFIA Project Consortium, Daniele Accornero, Aditya Agrawal, Isil Kibar Akilli, Omer Alamoudi, Maria Laura Alberti, Rasoul Aliannejad, Hamdan Aljahdali, Gina Amanda, Reut Anconina, Julio Daniel Antuni, Giuseppe Aquaro, Juan Arenas‐Jimenez, Bassey Asuquo, Iain Au‐Yong, Sergey Avdeev, Maurizio Balbi, Bruno Baldi, Elisabetta Balestro, Andrea Yu‐Lin Ban, Fotini Bardaka, Nicola Boscolo Bariga, Dhiraj Baruah, Ionela Belaconi, Elisabeth Bendstrup, David Bennett, Hans‐Christian Blum, Marialuisa Bocchino, Samuel De Bontridder, Andrea Borghesi, Demosthenes Bouros, Gracijela Bozovic, Pierre‐Yves Brillet, Marsel Broqi, John Bruzzi, Suryakala Buddha, Ivette Buendia‐Roldan, Carolina Cabo, Maria del Carmen Venero Caceres, Cristina Calandra, Roberto Calandriello, Diana Calaras, Jack Callum, Paula Campos, Roberto Carbone, Fabian Caro, Andre Carvalho, Marcelo Figueroa Casas, Eva Castaner, Jesus Javier Diaz Castanon, Cecilio Ceballos, Lorenzo Cereser, Veli Cetinsu, Gin Tsen Chai, Sachin Chaudhary, Nazia Chaudhuri, Chih‐Yu Chen, Patrick Alain Chui Wan Cheong, Giuseppe Cicchetti, Annemilia del Ciello, Alessandro Balbiano di Colcavagno, Sahary Conde, Pietro Costantini, Vincent Cottin, Davide Coviello, Diletta Cozzi, Dumitru Cravcenco, Giuseppe Cutaia, Rosa D’Abronzo, Gabriele D’Andrea, Marie‐Pierre Debray, Perla Delgado, Diemen Delgado‐Garcia, Alain Delobbe, Jane Dematte, Devesh J. Dhasmana, Sahajal Dhooria, Fotios Drakopanagiotakis, Dildar Duman, Chary Duraikannu, Glenn Eiger, Karim El‐Kersh, Samantha Ellis, Juan Ignacio Enghelmayer, Rosa Estrada‐Y‐Martin, Sherene Fakhran, Alessandra Farchione, Mary Jo Farmer, Alexia Farrugia, Leandro Fassola, Paola Faverio, Federico Felder, Maria Fernandez‐Velilla, Gilbert Ferretti, Justyna Fijolek, Francesco Filippone, Kevin Flaherty, Fabio Franco, Domenico Salvatore Gagliano, Amaia Urrutia Gajate, Clara Patricia Garcia, Andrea Estrada Garrido, Adrian Gaser, Bindu George, Subha Ghosh, Eddie Gibson, Hester Gietema, Rodrigo Gil, Beatriz Liliana Gil, Ritu Gill, Georgia Gkrepi, Raul Godoy, Athena Gogali, Nicole Goh, Alejandro Gomez, Aleksandar Grgic, Julien Guiot, H Henry Guo, Amit Gupta, Richard Hammond, Simon Hart, Thomas Hartman, Michael Henry, Nik Hirani, Wan Chin Hsieh, Killian Hurley, Charlotte Hyldgaard, Daniela Buklioska Ilievska, Marta Inchausti, Yoshikazu Inoue, Dominique Israel‐Biet, Maham Jehangir, Kerri Johannson, Takeshi Johkoh, Janet Johnston, Fortunato Juarez‐Hernandez, Soma Jyothula, Yasemin Kabasakal, Meena Kalluri, Can Zafer Karaman, Peter Kardos, Sandeep Katiyar, Ravindra Kumar Kedia, Lan‐Chau Kha, Nasreen Khalil, Mohammad Ayaz Khan, Yet H. Khor, Arda Kiani, Tomoo Kishaba, Heiko Knoop, Umut Knoop, Jane Ko, Eva Kocova, Lykourgos Kolilekas, Yasuhiro Kondoh, Chi Wan Koo, Vasileios Kouranos, Martijn de Kruif, Melahat Kul, Ozlem Ozdemir Kumbasar, Ronald Kuzo, Hoi Yee Kwan, Sebastien Van Laethem, Nicholas Landini, David Lang, Anna Rita Larici, Esther Law, Roberta Eufrasia Ledda, Ivo van der Lee, Yunkai Li, Valencia Lim, Randolph Lipchik, Su Ying Low, Fabrizio Luppi, Foteini Malli, Milena Adina Man, Eliane Mancuzo, Silvina Mannarino, George Margaritopoulos, Cristina Marrocchio, Manuela Martinez‐Frances, Toshiaki Matsuda, Federico Mei, Mayra Mejia, Veronica Menardi, Mikel Mendoza, Aravind Menon, Patricia Lopez Miguel, Ruxandra‐Iulia Milos, Paul Minnis, Atsushi Miyamoto, Nesrin Mogulkoc, Maria Molina‐Molina, Michele Mondoni, Zsuzsanna Monostori, Brian Morrissey, Marta Garcia Moyano, Mathias Andreas Mueller, Suranjan Mukherjee, Carlos F. Munoz‐Nunez, Daniel Musetescu, Prasanth Nair, Anoop Nambiar, Kiran Vishnu Narayan, Hrudaya Nath, Yuichiro Nei, Alexandra Neves, Boon Hau Ng, Tilo Niemann, Luca Novelli, Lubov Novikova, Paschalis Ntolios, Hilario Nunes, Takashi Ogura, Shinichiro Ohshimo, Anastasia Oikonomou, Maria Otaola, Marieke Overbeek, Lekshmi Padmakumari, Stefano Palmucci, Vijaya Kumary Baskara Pandian, Eftsratios Panselinas, Ilias Papanikolaou, Alessio Pascheale, Shital Patil, Wagner Diniz de Paula, Michael Perch, Raoul Pereira, Olof Joakim Pettersson, Sara Piciucchi, Wojciech Piotrowski, Roberta Polverosi, Daniel Popa, Ana Sofia Porta, Marta Posada, Thomas Skovhus Prior, Ilaria Pulzato, Mosleh Al Raddadi, Pailin Ratanawatkul, Gaetano Rea, Cristina Reichner, Pilar Rivera‐Ortega, Jonathan Rodrigues, Rui Rolo, Shigeki Saito, Yoana Lazaro Salazar, Mauricio Salinas, Mayra Alexandra Samudio, Pradosh Kumar Sarangi, Sayan Sarkar, Yuki Sato, Recep Savas, Simone Scarlata, Nicola Schembri, Thies Hendrik Schroeder, Alfredo Sebastiani, Palmi Shah, Aruna Shanmuganathan, Claudio Silva, Hans Slabbynck, Philip Slocum, Annemiek Snoeckx, Eman Sobh, Chun Ian Soo, Celia Sousa, Mark Spears, Irina Strambu, Emilia Maria Swietlik, Anne‐Marie Sykes, Pablo Szwarstein, Gabriela Tabaj, Yoshinori Tanino, Kiminobu Tanizawa, Adam Domonkos Tarnoki, David Laszlo Tarnoki, Felicia Teo, Weiping Tham, Fernando Tirapegui, Ryuichi Togawa, Claudia Lucia Toma, Sara Tomassetti, Keisuke Tomii, Hiromi Tomioka, Ioannis Tomos, Abdelfattah Touman, Sergio Trujillo, Vasilios Tzilas, Argyris Tzouvelekis, Marcela Usandivaras, Clara Valsecchi, Francesco Varone, Gerson Velasquez‐Pinto, Oksana Viltsaniuk, Yagnang Vyas, Yuko Waseda, Yuranga Weerakkody, Margaret Wilsher, Wim Wuyts, Oleh Yakovenko, Esteban Zirulnik, Maurizio Zompatori   +313 more
wiley   +1 more source

Determinants of Improved Dyspnea and Exercise Tolerance With Nasal High‐Flow O2 Therapy in Fibrotic Interstitial Lung Disease: A Pilot Physiological Study

Respirology, EarlyView.
We tested the respective effect of high‐flow and supplemental O2 from nasal high‐flow O2 therapy (NHFO2) on dyspnea and exercise tolerance in fibrotic interstitial lung disease. Supplemental O2 and NHFO2 (but not high‐flow) provided improvements in these outcomes at “iso‐O2 saturation” due to reduced ventilatory requirements.
Sarah Thivent, Marylise Ginoux, Samuel Verges, Frédéric Hérengt, Mathieu Marillier   +4 more
wiley   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source