Results 141 to 150 of about 1,177,456 (242)

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2692-2707, December 2026.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins, Tiziano Pramparo, Chaowapong Jarasvaraparn, Michael J. Wilsey, Voytek Slowik, Lakshmi Kunam, Janis M. Stoll, Ruben E. Quiros‐Tejeira, Simon Lam, Wikrom Karnsakul   +9 more
wiley   +1 more source

Research on the role and mechanism of SLC7A5 in idiopathic pulmonary fibrosis. [PDF]

Mol Med Rep
Wang M, Yu Y, Liu Z, Xu D, Li Y, Zou X, Shan N, Liu X, Shi C, Chen H.   +9 more
europepmc   +1 more source

An Anatomist's View on the Crosstalk Between the Liver and the Lung

Comprehensive Physiology, Volume 16, Issue 6, December 2026.
The liver and the lung have a similar three‐dimensional and cellular architecture as well as functional communalities. The structural, functional, and pathophysiological interplay between both organs suggests the existence of an interorgan axis, the liver‐lung axis. Created in biorender.com.
Tanja Kloock, Julia Schipke, Christian Mühlfeld   +2 more
wiley   +1 more source

Sex-related transcriptomic differences in idiopathic pulmonary fibrosis. [PDF]

Am J Respir Crit Care Med
Menon AA, Moll M, Pugashetti JV, Linderholm AL, Liu GY, Krishna R, Ma SF, Noth I, Hunninghake GM, Feghali-Bostwick C, Ghosh AJ.   +10 more
europepmc   +1 more source

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang, Songhang Xing, Shanshan Zhang, Yuan Hao, Xiaojie Qu, Wurihan Bao, Manwei Hao, Han Sun, Mingyuan Dong, Huiling Zhang, Dan Huang, Yiqi Wang, Xuanjie Jiang, Xiaoyu Pu, Yanyan Chi, Xingtong Wang, Xuefeng Li   +16 more
wiley   +1 more source

Idiopathic pulmonary fibrosis: current treatment options and critical appraisal of nintedanib

, 2015
Francesco Bonella,1 Susanne Stowasser,2 Lutz Wollin3 1Interstitial and Rare Lung Disease Unit, Ruhrlandklinik, University Hospital, University of Duisburg-Essen, Essen, 2Boehringer Ingelheim Pharma GmbH & Co.
Bonella F, Wollin L, Stowasser S
core  

International comparative epidemiology of idiopathic pulmonary fibrosis [PDF]

Background Evidence from the UK suggests the incidence of idiopathic pulmonary fibrosis is increasing, but there is a lack of data from elsewhere in the World. The cause of the disease remains unknown.
Hutchinson, John
core   +2 more sources

A regulatory network underlying idiopathic pulmonary fibrosis. [PDF]

Front Immunol
Li G, Pan X, Wang Y, Lan P, Li J, Wu X, He Y, Wen H, Cheng Z, Du Q, Wu W.   +10 more
europepmc   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, Volume 117, Issue 6, Page 1485-1499, December 2026.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Identification of a conserved sequence of disease progression in idiopathic pulmonary fibrosis. [PDF]

Am J Respir Crit Care Med
Huang X, Wu P, Guttentag AR, Quintana M, Kropski JA, Blackwell TS, Salisbury ML.   +6 more
europepmc   +1 more source