Results 131 to 140 of about 106,594 (302)

Comparison of Retrospective Motion Compensation Techniques for Pulmonary Dynamic Ultrashort Time to Echo MRI in Suspected Idiopathic Pulmonary Fibrosis

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Motion can degrade image quality during Ultrashort Time‐to‐Echo (UTE) pulmonary MRI and is particularly prevalent in patients with lung disease. Comprehensive assessment of the impact of motion compensation techniques on image quality and clinical interpretation is needed.
Abhilash S. Kizhakke Puliyakote, Luis A. Torres, Aiah AlAtoum, Natally AlArab, Kevin M. Johnson, Rodrigo M. Bello, Bryan O'Sullivan‐Murphy, Joseph G. Mammarappallil, Andrew D. Hahn, Sean B. Fain   +9 more
wiley   +1 more source

Exploring the Clinical Potential of Dynamic Digital Radiography: A Narrative Review

Journal of Medical Radiation Sciences, EarlyView.
Dynamic Digital Radiography (DDR) is a promising X‐ray technology that captures rapid image sequences, enabling the visualisation of moving anatomical structures for various clinical applications, including pulmonary, cardiac and orthopaedic assessments.
Connor W. Braniff, Mohamed K. Badawy
wiley   +1 more source

Differentiation Syndrome and Sweet Syndrome‐Like Overlap Following Venetoclax–Azacytidine and G‐CSF Therapy

JEADV Clinical Practice, EarlyView.
ABSTRACT Differentiation syndrome (DS) and Sweet syndrome (SS) are inflammatory complications mediated by cytokine dysregulation, classically associated with therapies that promote myeloid differentiation or cytokine release. While DS has been primarily linked to all‐trans retinoic acid (ATRA) and IDH inhibitors, recent evidence suggests that ...
Katerina Grafanaki, Maria Gerbesi, Zoe Apalla, Dimitrios Tsokanas, Efstathia Pasmatzi, Alexandros Spyridonidis, Maria Liga   +6 more
wiley   +1 more source

Prediction of progression in idiopathic pulmonary fibrosis using CT scans atbaseline: A quantum particle swarm optimization - Random forest approach [PDF]

, 2019
Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease characterized by an unpredictable progressive declinein lung function. Natural history of IPF is unknown and the prediction of disease progression at the time ofdiagnosis is notoriously ...
Brown, Matthew S., Goldin, Jonathan G., Kim, Grace Hyun J., Shi, Yu, Wong, Weng Kee   +4 more
core  

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan, Rui Zhang, Yu‐er Li, Rui Li, Shao‐bo Ge, Jin Liu, Shi‐yuan Yao, Xia Yang, Tao Zhang, Ming Zhang   +9 more
wiley   +1 more source

Telomerase and idiopathic pulmonary fibrosis

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2012
Idiopathic pulmonary fibrosis (IPF) is the most common manifestation of telomere-mediated disorders. Germline mutations in the essential telomerase genes, hTERT and hTR, are the causal genetic defect in up to one-sixth of pulmonary fibrosis families. The presence of telomerase mutations in this subset is significant for clinical decisions as affected ...
openaire   +2 more sources

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen, Nien‐Jung Chen, Chuan‐Yen Sun, Wen‐Kuang Yu, Vincent Yi‐Fong Su, Wan‐Ling Yang, Wei‐Chih Chen, Kuang‐Yao Yang   +7 more
wiley   +1 more source

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng, Yen‐Hsien Wu, Yi‐Ching Liu, I‐Chen Chen, Chung‐Yu Yeh, Shang‐En Huang, Ren‐Long Jan, Jwu‐Lai Yeh, Jong‐Hau Hsu   +8 more
wiley   +1 more source

Systemic Immunosuppression to Reduce Surgical Intervention in ANCA‐Negative Subglottic Stenosis

The Laryngoscope, EarlyView.
Idiopathic subglottic stenosis (iSGS) typically follows an indolent course managed with surgical dilatation, though a subset demonstrates aggressive, recurrent disease. In this retrospective cohort study, systemic immunosuppression significantly prolonged inter‐dilation intervals in both granulomatosis with polyangiitis‐associated SGS and an “atypical”
Guy Benshetrit, Stephen McAdoo, Romana Kuchai, Charles Pusey, Guri Sandhu, Chadwan Al‐Yaghchi   +5 more
wiley   +1 more source

Cochlear Implantation in Autoimmune Inner‐Ear Disease: Outcome and Patient‐Reported Benefit

The Laryngoscope, EarlyView.
This study demonstrates that patients with secondary autoimmune inner‐ear disease (AIED) achieve significant improvements in speech perception and quality of life following cochlear implantation. Although AIED patients may show slightly lower performance in noisy environments compared to controls, their subjective hearing benefit converges with matched
Merete Hartmann, David Oestreicher, Marc Albert Hüser, Dirk Beutner, Christian Wrobel   +4 more
wiley   +1 more source