Results 131 to 140 of about 1,177,456 (242)

International comparative epidemiology of idiopathic pulmonary fibrosis [PDF]

, 2017
Background\ud \ud Evidence from the UK suggests the incidence of idiopathic pulmonary fibrosis is increasing, but there is a lack of data from elsewhere in the World. The cause of the disease remains unknown.
Hutchinson, John
core  

Cisterna Chyli Dilation Is a Risk Factor for Liver Nodules and Hepatocellular Carcinoma in Fontan‐Associated Liver Disease: Pathophysiological Role of Lymphatic Dysfunction

Hepatology Research, EarlyView.
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto, Masatake Tanaka, Takeshi Goya, Yuuki Azuma, Tomonobu Hioki, Yusuke Morita, Keisuke Sakaguchi, Nobuhiro Fujita, Takamori Kakino, Ayako Ishikita, Kenichiro Yamamura, Ichiro Sakamoto, Kousei Ishigami, Kohtaro Abe, Yoshihiro Ogawa   +14 more
wiley   +1 more source

Unusual Giant Sialocyst Arising From Wharton's Duct: A Case Report

Oral Surgery, EarlyView.
ABSTRACT Background Head and neck masses in adults are a common reason for referral to maxillofacial surgeons and otolaryngologists, and most are benign. True salivary duct cysts (sialocysts) are extremely rare, accounting for < 1% of salivary duct lesions, and primarily involve minor salivary glands. Involvement of major salivary glands is exceptional,
Maksym Skrypnyk, Margarita Skikevych, Roman Skrypnyk, Volodymyr Mykytenko, Igor Skrypnyk, Liudmyla Voloshyna, Tetiana Yatsenko, Chun Xu, Satoshi Takahashi, Taro Osada, Koichi Hattori, Beate Heissig   +11 more
wiley   +1 more source

Safety of Pulsed Field Ablation: Established Evidence, Emerging Risks, and Knowledge Gaps

Pacing and Clinical Electrophysiology, EarlyView.
Overview of the safety profile of pulsed field ablation (PFA), highlighting established safety advantages, procedure‐related complications, electroporation‐specific effects, and key areas of ongoing uncertainty, particularly for ventricular applications.
Dakota de Cecco, Jeanne du Fay de Lavallaz, Boldizsar Kovacs, Jackson J. Liang   +3 more
wiley   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

Periodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem Esra Sahingur, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Impact of Letermovir on Voriconazole Concentrations in Lung Transplant Patients

Transplant Infectious Disease, EarlyView.
Concomitant letermovir was associated with lower voriconazole exposure and reduced attainment of commonly used efficacy thresholds in lung transplant recipients. Routine therapeutic drug monitoring after letermovir initiation is recommended, and empiric voriconazole dose escalation may be needed to avoid subtherapeutic exposure. ABSTRACT Background The
Leah Georgiades, Sunish Shah, Erin K. McCreary, Fernanda Silveira, Raman Venkataramanan, Vignesh Vasudevan, Ryan M. Rivosecchi   +6 more
wiley   +1 more source

A Case of Systemic Keratotic Disorders With Bark‐Like Appearance on the Dorsal Aspects of Both Feet

The Journal of Dermatology, EarlyView.
Kenta Morimoto, Sumire Ishino, Ken Watanabe   +2 more
wiley   +1 more source

Targeting pepsin provides superior protection to acid suppression in reflux‐associated airway inflammation and lung dysfunction

Experimental Physiology, EarlyView.
Abstract Gastro‐oesophageal reflux disease is a prevalent condition associated with extra‐oesophageal manifestations, such as pulmonary inflammation. Pepsin, an essential gastric enzyme, has been implicated in pulmonary complications owing to its inflammatory effects.
Thiago Meneses Araújo Leite Sales, Humberto Barbosa da Costa Filho, Kalinne Kelly Lima Gadelha, Kerolayne de Melo Nogueira, Álvaro Xavier Franco, Carlos Eduardo da Silva Monteiro, Maria Klayre Araújo de Sousa, Monalisa Cássias Souza, Isabele de Sá Silveira Melo, Lucas Antonio Duarte Nicolau, Marco Antonio de Freitas Clementino, Pedro Jorge Caldas Magalhães, Alexandre Havt, Pedro Marcos Gomes Soares, Daniel Sifrim, Marcellus Henrique Loiola Ponte de Souza   +15 more
wiley   +1 more source

Vascular and skeletal muscle oxidative capacity responses to continuous double and single leg cycling

Experimental Physiology, EarlyView.
Abstract The purpose of this work was to determine endothelial, microvascular, skeletal muscle oxidative capacity (SMOC) and cardiorespiratory responses to an acute bout of continuous single leg cycling (SLC) and double leg cycling (DLC). Ten recreationally active men and women volunteered to participate in this investigation and reported to the ...
Edward Z. Pelka, B. Ryan Davis, John McDaniel   +2 more
wiley   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source