European Journal of Heart Failure, EarlyView.Abstract Aims The aim of this study was to describe the prognostic importance of left ventricular ejection fraction (LVEF) versus right ventricular (RV) dilatation and dysfunction in patients with heart failure (HF) from countries of different income levels. Methods and results We enrolled 17 321 participants with HF from 40 countries.
Darryl P. Leong +16 more
wiley +1 more source
Journal of Cardiovascular Electrophysiology, Volume 33, Issue 12, Page 2585-2598, December 2022., 2022 Abstract Introduction Data on utilization, major complications, and in‐hospital mortality of catheter ablation (CA) for sarcoidosis‐related ventricular tachycardia (VT) are limited. We sought to determine the outcomes of sarcoidosis‐related VT, and incidence and predictors of complications associated with the CA procedure.
Jian Liang Tan +5 more
wiley +1 more source
Incidence, Prevalence, and Survival of Patients with Idiopathic Pulmonary Fibrosis in the UK. [PDF]
, 2018 INTRODUCTION: Recent developments in the care of patients with idiopathic pulmonary fibrosis have the potential to improve survival rates. Population-based estimates of the current disease burden are needed to evaluate the future impact of newly approved
Kausar, Imran +2 more
core +3 more sources
Global incidence and mortality of idiopathic pulmonary fibrosis: a systematic review
European Respiratory Journal, 2015 As idiopathic pulmonary fibrosis emerges as an important public health problem, there is a need to coordinate data on incidence and mortality globally.
John P Hutchinson +3 more
semanticscholar +1 more source
Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia
Exploration, EarlyView.We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley +1 more source
Journal of Internal Medicine, Volume 293, Issue 2, Page 130-143, February 2023., 2023 Abstract Since the beginning of the SARS‐CoV‐2 pandemic in 2020, researchers worldwide have made efforts to understand the mechanisms behind the varying range of COVID‐19 disease severity. Since the respiratory tract is the site of infection, and immune cells differ depending on their anatomical location, studying blood is not sufficient to understand ...
Sara Falck‐Jones +2 more
wiley +1 more source
B7-1, B7-2 and class II MHC molecules in idiopathic pulmonary fibrosis and bronchiolitis obliterans-organizing pneumonia [PDF]
, 2000 Y. Kaneko +5 more
openalex +2 more sources
Prognostic Model for Idiopathic Pulmonary Fibrosis Using Context-Aware Sequential-Parallel Hybrid Transformer and Enriched Clinical Information [PDF]
arXivIdiopathic pulmonary fibrosis (IPF) is a progressive disease that irreversibly transforms lung tissue into rigid fibrotic structures, leading to debilitating symptoms such as shortness of breath and chronic fatigue. The heterogeneity and complexity of this disease, particularly regarding its severity and progression rate, have made predicting its ...
arxiv
Idiopathic Pulmonary Fibrosis: Correlations between Bronchoalveolar Cellular Constituents and the Pathologic, Physiologic and Radiographic Features and Response to Treatment [PDF]
, 1989 S. H. Cho +9 more
openalex +1 more source
A poroelastic model coupled to a fluid network with applications in lung modelling [PDF]
arXiv, 2014 Here we develop a lung ventilation model, based a continuum poroelastic representation of lung parenchyma and a 0D airway tree flow model. For the poroelastic approximation we design and implement a lowest order stabilised finite element method. This component is strongly coupled to the 0D airway tree model. The framework is applied to a realistic lung
arxiv