Results 191 to 200 of about 1,177,456 (242)

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, Volume 81, Issue 11, Page 3825-3852, November 2026.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

IPF-RAG: temporal-aware retrieval-augmented generation for idiopathic pulmonary fibrosis care. [PDF]

Front Digit Health
Zheng X, Rui X, Long T, Wang L, Lv Z, Wang J, Jin Z, Huang W, Dong X, Wang Q, Dai Y.   +10 more
europepmc   +1 more source

Honokiol regulates Acute respiratory distress syndrome (ARDS)‐associated pulmonary fibrosis via the miR‐19a‐3p/POSTN axis

British Journal of Pharmacology, Volume 183, Issue 21, Page 6329-6351, November 2026.
Abstract Background and Purpose Acute respiratory distress syndrome (ARDS) and subsequent pulmonary fibrosis are associated with high mortality and limited treatment options. Periostin (POSTN) is a profibrotic mediator predicted to be regulated by microRNA‐19a‐3p (miR‐19a‐3p), but the relevance of this axis in ARDS‐associated pulmonary fibrosis remains
Weilun Liu, Hsiaohsuan Wang, Hsuanfu Kuo, Chiahung Yen, Modasang Hua, Chiayuan Chang, Zhiwei Xu, Ifan Liu, Chongchao Hsieh, Chihhsin Hsu, Chiayang Li, Shuchi Wang, Yunghsiang Chen, Menghsuan Cheng, Polen Liu   +14 more
wiley   +1 more source

Organelle Crosstalk and Metabolic Reprogramming in Idiopathic Pulmonary Fibrosis: Mechanisms and Therapeutic Implications. [PDF]

Cell Biochem Funct
Zhang Y, Teng L, Gong L, Fu Y, Qian M.
europepmc   +1 more source

Combined Pulmonary Fibrosis and Emphysema: Current Status and Future Perspective

The Clinical Respiratory Journal, Volume 20, Issue 11, November 2026.
This review summarizes recent advances in combined pulmonary fibrosis and emphysema (CPFE), proposing a novel etiologic classification framework encompassing four subtypes. We integrate a diagnostic algorithm to guide precise management and highlight emerging artificial intelligence strategies for risk stratification and dynamic prognostic assessment ...
Qinyu Deng, Chen Chen, Qinghe Zhang, Zilin Wei, Jianqi Sun, Feng Li   +5 more
wiley   +1 more source

Nationwide Incidence and Prevalence of Idiopathic Pulmonary Fibrosis in South Korea. [PDF]

Tuberc Respir Dis (Seoul)
Yoon HY, Kim KH, Kim SY, Park MS, Park JS, Park JH, Uh ST, Yoo JW, Lee JH, Choi WI, Lee JH, Han CH, Korea ILD Study Group.   +12 more
europepmc   +1 more source

Treprostinil: Mechanism of Action, Clinical, and Translational Science

Clinical and Translational Science, Volume 19, Issue 11, November 2026.
ABSTRACT Treprostinil is a synthetic prostacyclin analogue with a tricyclic benzindene structure that confers markedly enhanced metabolic stability relative to native prostacyclin, enabling delivery by four distinct routes—intravenous, subcutaneous, inhaled, and oral—that together constitute a mainstay of pharmacotherapy for pulmonary arterial ...
Muhammad Sameed, Muhammad Waleed, Veronika Colomy   +2 more
wiley   +1 more source

The role of glutamine metabolism in the pathogenesis of idiopathic pulmonary fibrosis and its therapeutic potential. [PDF]

Front Oncol
Li J.
europepmc   +1 more source

From Pattern Recognition to Decision Guidance: Artificial Intelligence in Interstitial Lung Disease Diagnosis and Surveillance

Respirology, Volume 31, Issue 11, Page 1070-1073, November 2026.
Deliang Yang, Xue Li, David Chi Leung Lam   +2 more
wiley   +1 more source

Mitochondrial Dysfunction as a Context‐Dependent Driver and Amplifier of the SASP: Targeting the mtDNA–cGAS–STING Axis for Next‐Generation Senotherapeutics

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Cellular senescence combines stable cell‐cycle arrest with mitochondrial and innate immune remodelling that shapes the senescence‐associated secretory phenotype (SASP). This narrative review evaluates mitochondrial dysfunction as a context‐dependent initiator or amplifier of senescence and examines mitochondrial DNA (mtDNA) sensing through ...
Hamza Kamaran Hama, Mohammed Ali Hama, Musa M. Zorab, Amirreza Gholami, Ammar Mohammed Al‐Farga   +4 more
wiley   +1 more source