Results 201 to 210 of about 106,594 (302)

Exploring the Lung–Liver Axis in Pulmonary Arterial Hypertension

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Among PAH patients without liver disease, subclinical liver dysfunction quantified by MELD‐Na associates with higher pulmonary vascular resistance and inflammatory activation of the pulmonary endothelium, characterized by an IL‐6‐centered transcriptional network enriched for leukocyte chemotaxis.
Navneet Singh, Jordan Lawson, Ashok Ragavendran, Somanshu Banerjee, Andy Hon, Alejandro Vega, Jason Hong, Christopher J. Mullin, Mandy Pereira, Allyson Sherman‐Roe, Alexander T. Jorrin, Tiffaney Cayton, Gregory Fishbein, James R. Klinger, William M. Oldham, Rui‐Sheng Wang, Zhiyu Dai, Michael Fallon, Elizabeth O. Harrington, Olin D. Liang, Soban Umar, Corey E. Ventetuolo   +21 more
wiley   +1 more source

Spatial Distribution of K13-Positive Airway Epithelial Cells in Idiopathic Pulmonary Fibrosis. [PDF]

Biomedicines
Teng F, Zheng Q, Bai Y, Zhao Q, Fu Y, Dai H, Huang C, Ren T.   +7 more
europepmc   +1 more source

Spatial transcriptomics reveals a new cluster of fibroblasts to promote the progression of lung adenocarcinoma

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
1. Spatial transcriptomics reveals two types of colocation patterns between lung cancer cells and fibroblasts in LUAD. SPP1+ TM4SF4+ epithelial cells and COL+ fibroblasts were co‐located in a highly malignant region, while SFTPC+ epithelial cells and DCN+ fibroblasts were in a low malignant region. 2.
Liyang Li, Xiaoxia Liu, Yifei Liu, Xuanqi Liu, Wanxin Duan, Yujia Jiang, Jian Chen, Tianxiang Chen, Gang Chen, Ao Chen, Duojiao Wu, Dongli Song, Yuanlin Song   +12 more
wiley   +1 more source

Epidemiology of idiopathic pulmonary fibrosis: a population registry-based study. [PDF]

Orphanet J Rare Dis
Francesca G, Michele S, Anna P, Paolo C, Davide C, Federico L, Francesco P, Elisabetta R, Laura T, Sara T, Carrozzi L, Elena B, Alessio C.   +12 more
europepmc   +1 more source

Modulation of Ferroptosis Biomarkers by Thinned Apple Polyphenols Extract in Acute and Chronic Lung Injuries

eFood, Volume 7, Issue 3, June 2026.
Thinned apple polyphenols (TAP) extract reduced ferroptosis in acute and chronic lung injuries. TAP activated Nrf2 and modulated key biomarkers (MDA, NOX4, GPX4, FTH1), leading to decreased inflammation and fibrosis. These findings suggest TAP as a potential therapeutic approach for lung injury through ferroptosis regulation. ABSTRACT Acute and chronic
Rosalba Siracusa, Alessia Arangia, Marika Cordaro, Roberta Fusco, Salvatore Cuzzocrea, Giancarlo Aldini, Daniela Impellizzeri, Rosanna Di Paola, Ramona D'Amico   +8 more
wiley   +1 more source

Deep-learning networks accurately detect pulmonary hypertension in patients with idiopathic pulmonary fibrosis. [PDF]

ERJ Open Res
Arvanitaki A, Diller GP, Lawrence A, Mukherjee B, Semple T, Kouranos V, Li W, Gatzoulis MA, Price LC, Wort SJ.   +9 more
europepmc   +1 more source

Mitochondrial reprogramming in lung cancer: a therapeutic vulnerability and a strategy for reversing drug resistance

The Journal of Pathology, Volume 269, Issue 2, Page 149-163, June 2026.
Abstract The conceptualization of mitochondria, previously restricted to their function as cellular ‘powerhouses’, has evolved to recognize their function as central coordinating hubs for the orchestration of cancer cell metabolism, signaling, and fate determination.
Woo Hyun Park
wiley   +1 more source

Survival in familial idiopathic pulmonary fibrosis and fibrotic hypersensitivity pneumonitis. [PDF]

Sarcoidosis Vasc Diffuse Lung Dis
Reis Estrella D, Mancuzo E, De Amorim Correa R, Tibana R, Soares MR, De Castro Pereira CA.   +5 more
europepmc   +1 more source

Joint modeling of longitudinal and time‐to‐event data for dynamic disease risk prediction using proteomics

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Biomedical studies increasingly incorporate longitudinal data, enabling us to track individual disease processes over time at the molecular level, and to discover associations of the molecular profiles with the outcome of interest, such as the onset of a disease.
Markus Lindén, Tea Ammunét, Tommi Välikangas, Laura L. Elo, Tomi Suomi   +4 more
wiley   +1 more source

Shortened Telomere Length as a Risk Factor for Idiopathic Pulmonary Fibrosis: A Meta-Analysis. [PDF]

Open Respir Med J
Fachrucha F, Syuaib FI, Purwono A, Nurwidya F, Andarini SL, Burhan E, Wiyono WH.   +6 more
europepmc   +1 more source