Gastroesophageal Reflux, Sleep-Disordered Breathing, and Outcomes in Patients With Idiopathic Pulmonary Fibrosis. [PDF]
Ellis B +11 more
europepmc +1 more source
Regulated Cell Death in Idiopathic Pulmonary Fibrosis
This graphical abstract illustrates regulated cell death (RCD) across key pulmonary cell types—including alveolar epithelial cells, fibroblasts, macrophages, and endothelial cells—modulated through a dynamic death modulation network within the IPF microenvironment.
Xiaoyue Pan +10 more
wiley +1 more source
Biomarkers of mitochondrial dynamics in idiopathic pulmonary fibrosis: Identification and validation through transcriptomic and single-cell analyses. [PDF]
Wang Y +5 more
europepmc +1 more source
Abstract Background Computed Tomography Ventilation Imaging (CTVI) is an investigational technique that has its basis in functional lung avoidance radiotherapy. It offers a cost‐effective and accessible alternative to nuclear medicine imaging by generating lung ventilation maps from 4DCT or paired inhale/exhale breath‐hold CT (BHCT) scans. Despite over
Jeremy Lim +4 more
wiley +1 more source
Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee +7 more
wiley +1 more source
Idiopathic pulmonary fibrosis predicts local recurrence following surgery in patients with non-small cell lung cancer. [PDF]
Maeda R +3 more
europepmc +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Idiopathic Pulmonary Fibrosis: Analysis of Predisposing Variants in Patients with Familial Forms. [PDF]
Stanghellini I +13 more
europepmc +1 more source
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo +10 more
wiley +1 more source

