Results 221 to 230 of about 106,594 (302)

Gastroesophageal Reflux, Sleep-Disordered Breathing, and Outcomes in Patients With Idiopathic Pulmonary Fibrosis. [PDF]

open access: yesCan Respir J
Ellis B   +11 more
europepmc   +1 more source

Regulated Cell Death in Idiopathic Pulmonary Fibrosis

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
This graphical abstract illustrates regulated cell death (RCD) across key pulmonary cell types—including alveolar epithelial cells, fibroblasts, macrophages, and endothelial cells—modulated through a dynamic death modulation network within the IPF microenvironment.
Xiaoyue Pan   +10 more
wiley   +1 more source

Investigating the impact of key algorithm parameters and patient‐specific factors on the accuracy of CT ventilation imaging

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 5, May 2026.
Abstract Background Computed Tomography Ventilation Imaging (CTVI) is an investigational technique that has its basis in functional lung avoidance radiotherapy. It offers a cost‐effective and accessible alternative to nuclear medicine imaging by generating lung ventilation maps from 4DCT or paired inhale/exhale breath‐hold CT (BHCT) scans. Despite over
Jeremy Lim   +4 more
wiley   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 17, 8 May 2026.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee   +7 more
wiley   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin   +11 more
wiley   +1 more source

Idiopathic Pulmonary Fibrosis: Analysis of Predisposing Variants in Patients with Familial Forms. [PDF]

open access: yesBiomedicines
Stanghellini I   +13 more
europepmc   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo   +10 more
wiley   +1 more source

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