Results 231 to 240 of about 73,124 (298)

Comorbidity in Patients with Idiopathic Pulmonary Fibrosis: Evaluation Using the Charlson, TORVAN and GAP Indices. [PDF]

J Clin Med
Torres Tienza S, de Miguel-Díez J, Ortega CG, Jareño Esteban JJ.   +3 more
europepmc   +1 more source

Evidence for a Two‐Step Model for Activation of GPR25 by the Chemoattractant CXCL17

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT CXCL17 was recently reported to activate GPR25, a receptor expressed by T‐regulatory cells. Although classified as a chemokine, the activity of CXCL17 is ablated by minor C‐terminal truncation, suggesting a novel mode of receptor activation. We set out to test this hypothesis by mutagenesis. GPR25 was expressed in the murine pre‐B cell line L1.
Wuqing Yang, Sean P. Giblin, James E. Pease   +2 more
wiley   +1 more source

Causal and shared genetic insights into severe COVID-19 and idiopathic pulmonary fibrosis. [PDF]

iScience
Lin S, Dang X, Kou X, Zhang X, Ding X, Li X.   +5 more
europepmc   +1 more source

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

Cell Proliferation, Volume 59, Issue 7, July 2026.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang, Ling Rao, Xiaofang Li, Miaofen Zhang, Huiting Huang, Zhiyan Luo, Gang Liao, Yong Jiang, Shaofeng Zhan, Qiong Liu, Xiufang Huang   +10 more
wiley   +1 more source

Impact of indoor exposure to particulate matter on the progression of idiopathic pulmonary fibrosis: a prospective multicentre cohort study protocol. [PDF]

BMJ Open Respir Res
Yoon HY, Oh JH, Choi WI, Choi SM, Park J, Jo YS, Park SW, Lee JH, Lee HK, Kim SY, Woo A, Kim YH, Yoo H, Park JS, Kang HK, Kang JE, Park JH, Kim WJ, Kim KN, Song JW.   +19 more
europepmc   +1 more source

Feasibility, Safety and Outcomes of Early Mobilization in the ICU Following Lung Transplantation: A Scoping Review

Clinical Transplantation, Volume 40, Issue 7, July 2026.
ABSTRACT Background Lung transplantation (LTx) is performed in approximately 4500 patients worldwide each year. Postoperatively, patients are at high risk of muscle catabolism due to Intensive Care Unit (ICU)‐acquired weakness, potentially compromising functional recovery. While post‐LTx rehabilitation is usually initiated after hospital discharge, the
Matthieu Reffienna, Adéla Foudhaïli, Jonathan Messika, Damien Vitiello   +3 more
wiley   +1 more source

The Role of DLNO in the Functional Assessment of Patients with Idiopathic Pulmonary Fibrosis. [PDF]

Medicina (Kaunas)
Tondo P, Ora J, Natale MP, Scioscia G, Zerillo B, Di Maggio MS, Rogliani P, Lacedonia D.   +7 more
europepmc   +1 more source

An update on the landscape of collagen bioactive fragments

The FEBS Journal, Volume 293, Issue 13, Page 4064-4084, July 2026.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Stiffness-dependent alveolar type II cell senescence in idiopathic pulmonary fibrosis. [PDF]

Cell Commun Signal
Lin CR, Woranam K, Hayek H, Jeger J, Karim L, Kosmider B, Kaminski R, Schultz CW, Bolla S, Marchetti N, Criner GJ, Bahmed K.   +11 more
europepmc   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, Volume 293, Issue 13, Page 3758-3787, July 2026.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source