Results 231 to 240 of about 106,594 (302)

Identification of Notch pathway-related biomarkers in patients with idiopathic pulmonary fibrosis. [PDF]

PLoS One
Yang S, Bao Y, Zhao H, Zhang C, Wang Y, Li K, Li P, Zhang W, Zhu X.   +8 more
europepmc   +1 more source

Severe Occupational Hypersensitivity Pneumonitis: A Case Series of Four Patients Requiring Lung Transplantation

American Journal of Industrial Medicine, Volume 69, Issue 5, Page 323-334, May 2026.
ABSTRACT Hypersensitivity pneumonitis (HP) is an immune‐mediated interstitial lung disease triggered by repeated inhalation of organic or chemical antigens. Occupational exposures account for approximately 19% of all cases. Early diagnosis, identification of the responsible antigen(s), and immediate avoidance of exposure are crucial to prevent ...
Ludwig Frei‐Stuber, Judith Mohren, Ester Mau, Bernhard Werner, Rudolf A. Hatz, Jürgen Barton, Dennis Nowak   +6 more
wiley   +1 more source

Decoding the ubiquitination-immunity axis in idiopathic pulmonary fibrosis: diagnostic insights and therapeutic implications. [PDF]

Respir Res
He W, Feng C, Liu M, Qin H, Wu Y, Deng C, Zhu X.   +6 more
europepmc   +1 more source

Single‐port robot‐assisted ureterolysis for retroperitoneal fibrosis: A less invasive path to functional recovery

BJUI Compass, Volume 7, Issue 5, May 2026.
Abstract Objective The objective of this study is to evaluate the outcomes of an initial series of single‐port robot‐assisted ureterolysis (SP‐RAU) in patients with retroperitoneal fibrosis (RPF). Patients and Methods We prospectively collected surgical and clinical data from all consecutive patients undergoing SP‐RAU at our institution between April ...
Filippo Carletti, Alexandru Turcan, Flavia Tamborino, Luca Alfredo Morgantini, Lorenzo Salvodirocco, Marwan Alkassis, Fabrizio Dal Moro, Simone Crivellaro   +7 more
wiley   +1 more source

Antifibrotic therapy in familial idiopathic pulmonary fibrosis: a comparative cohort study. [PDF]

Sci Rep
Morikawa K, Suzuki Y, Kato S, Kono M, Hashimoto D, Yokomura K, Inoue Y, Yasui H, Hozumi H, Karayama M, Furuhashi K, Enomoto N, Fujisawa T, Inui N, Suda T.   +14 more
europepmc   +1 more source

Randomized Phase 1 Studies Evaluating the Safety, Tolerability, Pharmacokinetics, and Target Occupancy of Zampilimab in Healthy Participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 5, May 2026.
Abstract Zampilimab (UCB7858) is a humanized monoclonal immunoglobulin G4P, transglutaminase 2 (TG2) inhibiting antibody. We investigated safety, tolerability, pharmacokinetics, and target occupancy of zampilimab (intravenous ≤2000 mg; subcutaneous ≤1000 mg) in healthy participants in a randomized, placebo‑controlled, single‐ascending‐dose Phase 1 ...
Jo Collier, Rowann Bowcutt, Geoffrey I. Johnston, Jane Y. C. Chan, Anastasiia Raievska, Alison Bigley, Richard Nicholl, Tim S. Schmidt, Maria Sarno, Zahid Ali, Elizabeth Thomson   +10 more
wiley   +1 more source

Obacunone Targets Serine–Threonine Kinase Receptor–Associated Protein to Promote the Formation of the TGF‐β/Smad7 Complex and Ameliorates Bleomycin‐Induced Pulmonary Fibrosis

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Pulmonary fibrosis (PF) is a complex and fatal interstitial lung disease in which the TGF‐β/Smad signaling pathway plays a pivotal role in fibrotic progression. However, strategies for precise modulation of this pathway remain limited. In this study, a bleomycin (BLM)‐induced mouse model of PF and TGF‐β‐stimulated MLE‐12 or primary lung ...
Yonghu Chen, Hongzhen Chen, Guangxi Li, Ning Li, Xuezheng Li, Zhe Jiang   +5 more
wiley   +1 more source

FTIR imaging identifies alterations in lung tissue structure and biochemical composition in human idiopathic pulmonary fibrosis. [PDF]

Sci Rep
Miller LM, Kipshidze G, Meka SR, Molina I, Feghali-Bostwic C, Bandela M, Natarajan V, Suryadevara V.   +7 more
europepmc   +1 more source

Magnetocardiography combined with machine learning for pulmonary hypertension detection and improved short‐term risk assessment

Interdisciplinary Medicine, Volume 4, Issue 3, May 2026.
Magnetocardiography (MCG) enables non‐invasive mapping of cardiac magnetic fields. In this study, an MCG‐based machine learning model detects pulmonary hypertension with robust performance. Furthermore, MCG features may improve the accuracy of short‐term risk assessment.
Yuankun Qi, Jiaqi Liang, Kai Ma, Xiaoyu Hu, Yu Zhang, Xiaole Han, Dong Xu, Xu Zhang, Xiaopei Cui, Min Xiang, Hongyu Zhang, Jiancheng Fang   +11 more
wiley   +1 more source