Results 211 to 220 of about 999,769 (295)

Histone Post‐Translational Modifications Regulating Ferroptosis: The Molecular Mechanisms and Disease Associations

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Ferroptosis is a form of programmed cell death characterized by iron‐dependent phospholipid peroxidation and is implicated in a wide range of human diseases. Emerging evidence highlights the critical role of epigenetic regulation in this process.
Xiaoqian Tang, Haodang Luo, Siqi Gao, Xiaocheng Liu, Qing Sun, Yanhua Zeng   +5 more
wiley   +1 more source

A biomarker-guided framework for corticosteroid treatment stratification in acute exacerbation of idiopathic pulmonary fibrosis. [PDF]

Front Pharmacol
Chen Q, Zhang Y, Li J, Zhu Q, Wang Z, Wen X.   +5 more
europepmc   +1 more source

Management of Massive Post‐Tracheostomy Subcutaneous Emphysema With an Adjustable‐Length, Wire‐Reinforced Tracheostomy Tube: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Massive subcutaneous emphysema with pneumomediastinum is a rare but potentially life‐threatening complication following tracheostomy, for which standardized management strategies are lacking. We report the case of a 67‐year‐old man who developed progressive cervicofacial and thoracic subcutaneous emphysema on postoperative Day 9 after an ...
Omar Aboul Hosn, Rita Khattar, Jaafar A. Hadi, Gabriel Dunya, Sami Jean Melki   +4 more
wiley   +1 more source

Multiomic analysis identifies T cell subsets and mechanisms of epithelial interaction in idiopathic pulmonary fibrosis. [PDF]

JCI Insight
Serezani AP, Bazzano JM, Pascoalino BD, da Silva L, Dietrich AJ, Taylor CJ, Sherrill T, Vannan A, Calvi CL, Gonzalez-Ericsson PI, Wilfong EM, Bacchetta M, Shaver CM, Ware LB, Salisbury ML, Van Kaer L, Banovich NE, Kropski JA, Blackwell TS.   +18 more
europepmc   +1 more source

Mechanobiological feedback loops and quantitative decision thresholds in organ fibrosis: Translational principles for antifibrotic therapy

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Multiorgan fibrosis arises when chronic injury activates fibroblasts and remodels extracellular matrix, whose increasing stiffness sustains disease through mechanotransduction pathways. Bidirectional cellular‐matrix feedback operates across lung, heart, liver, and kidney.
Amedeo Lonardo, Ralf Weiskirchen
wiley   +1 more source

Artificial intelligence chatbots and idiopathic pulmonary fibrosis: are they ready to inform patients? [PDF]

Rev Assoc Med Bras (1992)
Şenel MY, Ayan E, Çolak M, Çoban H, Erel F, Sarıoğlu N.   +5 more
europepmc   +1 more source

From Executor to Orchestrator: The Pharmacology Scientist in the Age of Agentic AI

Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 648-662, September 2026.
Drug development productivity has not improved despite five decades of computational advancement, with the probability that a compound entering Phase I achieving regulatory approval remaining near 10%. Each automation wave increased throughput while leaving the interpretive bottleneck intact; scientists continued to formulate questions, evaluate ...
Michael McCoy, Matthew McCoy
wiley   +1 more source

Inhaled LTI-03 for idiopathic pulmonary fibrosis: a randomized dose escalation study. [PDF]

Nat Commun
Molyneaux PL, Hirani NA, Chia CCK, Kulkarni T, Zaman T, Kaner RJ, Coelho AL, Jannini-Sa YAP, Windsor B, Kruger S, Christensen DJ, Shoemaker SA, Hogaboam CM, MacKenzie B, Günther A.   +14 more
europepmc   +1 more source

Dissecting Bone Marrow Fibrosis in Philadelphia‐Negative Myeloproliferative Neoplasms: Multiple Roads Lead to Rome

Hematological Oncology, Volume 44, Issue 5, September 2026.
ABSTRACT Philadelphia‐negative myeloproliferative neoplasms (MPN), a spectrum of blood malignancies characterized by uncontrolled myeloid proliferation, persist as a key challenge in onco‐hematology due to their intricate molecular background, heterogeneous clinical phenotypes, and variable prognoses.
Mariagiovanna Ballato, Vincenzo Fiorentino, Gabriele Ricciardi, Pietro Tralongo, Emanuela Germanà, Alessandro Allegra, Fabio Stagno, Guido Fadda, Maurizio Martini   +8 more
wiley   +1 more source

A CSF-1R Ig4-5 Domain-Targeting Antibody for the Treatment of Idiopathic Pulmonary Fibrosis. [PDF]

Antibodies (Basel)
Luo W, Shao Z, Wang T, Lok K, Zhang R, Li Y.   +5 more
europepmc   +1 more source