Acquired whole-lung mismatched perfusion defects on pulmonary ventilation/perfusion scintigraphy [PDF]
Alberg +7 more
core +2 more sources
Advances in Erectile Dysfunction Management: What Does Work
ABSTRACT Erectile dysfunction (ED) is a prevalent and multifactorial disorder that substantially affects quality of life. Pathophysiology includes vascular, neurogenic, drug‐induced, and psychogenic causes, and frequently coexists with cardiometabolic disease.
Jolie Shen +3 more
wiley +1 more source
Monoallelic PARN mutation presenting as pancytopenia, hepatic fibrosis and idiopathic pulmonary fibrosis. [PDF]
Soni J, Sam KS, Taneja V, Khosla P.
europepmc +1 more source
In this study, nintedanib reduced lung fibrosis in a rat double‐hit bleomycin‐induced model. Transcriptomic analysis revealed two key gene signatures related to the effect of the molecule: one involving mesenchymal cells affecting known fibrotic pathways and another linking mainly macrophages to lipid metabolism.
Martina Bonatti +14 more
wiley +1 more source
Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease
This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley +1 more source
Tweaking the Complex Fibrogenic Role of Lymphocytes in Idiopathic Pulmonary Fibrosis. [PDF]
Bhattacharyya A, Saba JD.
europepmc +1 more source
Bilateral versus single lung transplantation: Are two lungs better than one? [PDF]
Meyers, Bryan F, Subramanian, Melanie P
core +1 more source
Dilated Cardiomyopathy and Aortic Thrombosis in a Capuchin Monkey (Sapajus apella)
ABSTRACT This case report describes a capuchin monkey (Sapajus apella) that presented with bilateral paralysis and cold hind limbs. Clinical examination, including ultrasound imaging, revealed dilated cardiomyopathy and aortic thrombosis. Macroscopic, histopathological, and immunohistochemical analyses confirmed these findings.
Christiane Helm +3 more
wiley +1 more source
Wnt3-mediated fibrosis and carcinogenesis of lung squamous cell carcinoma in idiopathic pulmonary fibrosis. [PDF]
Matsuoka A +24 more
europepmc +1 more source
Molecular Clocks in Translational Roadmap for Circadian‐Based Therapeutics in Lung Diseases
High‐amplitude circadian oscillations maintain lung immune and epithelial homeostasis. Chronic inflammation dampens peripheral clock amplitude, driving chronodisruption, barrier dysfunction, and remodeling. Clock‐targeted therapies re‐entrain the lung circadian clock, restore rhythmic immune resolution, and promote functional lung repair.
Kingshuk Panda +5 more
wiley +1 more source

