Results 251 to 260 of about 95,044 (332)

From Liver Insights to Lung Innovations: FGF21 and Idiopathic Pulmonary Fibrosis. [PDF]

open access: yesAm J Respir Crit Care Med
Gonzalez Coba AJ, Barnes JW, Krick S.
europepmc   +1 more source

Targeting PDK1: A novel approach to combat hypoxia‐induced epithelial‐mesenchymal transition in chronic rhinosinusitis with nasal polyps

open access: yesClinical and Translational Allergy, Volume 15, Issue 4, April 2025.
Abstract Background Hypoxia is a prevalent pathological process in chronic rhinosinusitis with nasal polyps (CRSwNP), leading to a cascade of pathological events, including epithelial‐mesenchymal transition (EMT). However, the mechanisms underlying hypoxia‐induced EMT remain unclear. This study aims to elucidate the mechanisms driving EMT under hypoxic
Sicen Pan   +7 more
wiley   +1 more source

Impairments and prognostic factors for survival in patients with idiopathic pulmonary fibrosis

open access: bronze, 2003
Keisuke Miki   +6 more
openalex   +1 more source

Progress, Pitfalls, and Impact of AI‐Driven Clinical Trials

open access: yesClinical Pharmacology &Therapeutics, Volume 117, Issue 4, Page 887-890, April 2025.
Since the deep learning revolution of the early 2010s, significant efforts and billions of dollars have been invested in applying artificial intelligence (AI) to drug discovery and development (AIDD). However, despite high expectations, few AI‐discovered or AI‐designed drugs have entered human clinical trials, and none have achieved clinical approval ...
Dominika Wilczok, Alex Zhavoronkov
wiley   +1 more source

Cyclosporin A Followed by the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis with Corticosteroid

open access: bronze, 2003
Naohiko Inase   +7 more
openalex   +1 more source

Blood Cell Counts and Inflammatory Indexes in Idiopathic Pulmonary Fibrosis. [PDF]

open access: yesCureus
Ay D   +5 more
europepmc   +1 more source

Diverse potential of chimeric antigen receptor‐engineered cell therapy: Beyond cancer

open access: yesClinical and Translational Medicine, Volume 15, Issue 4, April 2025.
1. In theory, CAR‐engineering therapy can achieve therapeutic effects by targeting cells expressing specific antigens and thereby eliminating or regulating disease‐related cell subpopulations. 2. Although CAR‐engineering therapy is currently only approved for the treatment of cancer, it has also shown potential in non‐tumour diseases. 3.
Lvying Wu, Lingfeng Zhu, Jin Chen
wiley   +1 more source

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