Results 261 to 270 of about 195,645 (350)
Epstein–Barr virus and wild p53 in idiopathic pulmonary fibrosis
She Lok+4 more
openalex +1 more source
Glutamine Metabolism: Molecular Regulation, Biological Functions, and Diseases
Tumor cells adapt to nutrient‐poor environments by altering metabolism to acquire essential nutrients. They convert glutamine into glutamate and α‐ketoglutarate, supporting mTOR activation and sugar biosynthesis. Disruption of mTORC1 signaling is linked to disease, while glutamine and leucine activation promotes cell growth and inhibits autophagy ...
Mudasir A. Kumar+10 more
wiley +1 more source
Insight into the efficacy and safety of pirfenidone: The treatment of idiopathic pulmonary fibrosis. [PDF]
Xu LY, Yu Y, Cen LS.
europepmc +1 more source
Autoimmune Diseases: Molecular Pathogenesis and Therapeutic Targets
This review provides a comprehensive overview of common autoimmune diseases, details clinical manifestations and summarizes the pathogenesis, including the breakdown of immune tolerance, initiation of autoimmune responses, and their progressive amplification.
Xiaoshuang Song+9 more
wiley +1 more source
ITGAV, a specific biomarker associated with the pathogenesis of idiopathic pulmonary fibrosis. [PDF]
Bi Z+6 more
europepmc +1 more source
Aberrant Wnt/β-Catenin Pathway Activation in Idiopathic Pulmonary Fibrosis [PDF]
Marco Chilosi+13 more
openalex +1 more source
ABSTRACT PH‐ILD carries a poor prognosis, particularly with PVR > 5 WU. The INCREASE trial demonstrated the successful use of inhaled treprostinil, but slow uptitration delays the effects. Our study suggests outpatient IV dobutamine as interim support, improving contractility and reducing PVR during uptitration.
A. Kumar+4 more
wiley +1 more source
Advances in idiopathic pulmonary fibrosis diagnosis and treatment. [PDF]
Liu H, Shen J, He C.
europepmc +1 more source
Practical Considerations for Managing Patients on Tyvaso DPI (Treprostinil Inhalation Powder)
ABSTRACT Pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH‐ILD) require a multifaceted, guideline‐directed management approach. This includes active patient participation in partnership with their healthcare team to minimize disease impact and improve survival.
Jennifer H. Keeley+8 more
wiley +1 more source