Ovarian Aging: Mechanisms, Age‐Related Disorders, and Therapeutic Interventions
A comprehensive overview of the molecular mechanisms underlying ovarian aging, its association with age‐related diseases, and potential therapeutic interventions. Ovarian aging involves DNA damage, mitochondrial dysfunction, oxidative stress, telomere attrition, and follicular depletion, driving age‐related infertility, menopause, and multiple systemic
Xingyu Liu +4 more
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Proteomic Biomarkers of Survival in Non-Idiopathic Pulmonary Fibrosis Interstitial Lung Disease. [PDF]
Alqalyoobi S +17 more
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Musculoskeletal Diseases: Mechanisms and Therapeutic Advances
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma +17 more
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MUC5B Polymorphism and Susceptibility to Idiopathic Pulmonary Fibrosis in Morocco. [PDF]
Senhaji L +12 more
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Prognostic significance of HALP score in İdiopathic Pulmonary Fibrosis-related mortality. [PDF]
Çolak M +4 more
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Baihe Gujin Decoction Attenuates Idiopathic Pulmonary Fibrosis Via Regulating Proline Metabolism
Hua Wu +5 more
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Immunological Similarities and Differences between Post-COVID-19 Lung Sequelae and Idiopathic Pulmonary Fibrosis [PDF]
Sara Gangi +7 more
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Mechanical Signaling: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets
In this review, we summarize cell–ECM interactions and delve into the complex mechanotransduction. We introduce advanced research methods and emerging clinical tools used to study cellular mechanical phenotypes, mechanotransduction, and disease progression. Additionally, we analyze the role of mechanical biomarkers in the development and progression of
Yicen Long +5 more
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Emerging Concepts in Therapeutic Interventions for Idiopathic Pulmonary Fibrosis. [PDF]
Schott CA, Mohning MP, Cooley JC.
europepmc +1 more source
Alternative splicing (AS) expands proteomic diversity and functional complexity in eukaryotes, regulated by spliceosomal components, RNA elements, and epigenetic modifications. Dysregulated AS contributes to diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions, among others. Therapeutic interventions, such as antisense
Zhi‐Min Zhu +5 more
wiley +1 more source

