Results 21 to 30 of about 13,654 (259)

Common polymorphisms of growth hormone: Growth hormone receptor axis in Turkish children with short stature [PDF]

, 2022
Objective: A single-nucleotide polymorphism of the growth hormone 1 gene, GH1IVS4+90A>T (rs2665802), associated with short stature and a polymorphism of the growth hormone receptor gene, exon 3 deleted variant, associated with increased responsiveness to
Adal, Servet Erdal, Buyru, Ayşe Nur, Deviren, Ayhan, Ercan, Oya, Yıldız, Metin, Yılmaz Güleç, Elif   +5 more
core   +1 more source

Serum Metabonomics Reveals Key Metabolites in Different Types of Childhood Short Stature

Frontiers in Pharmacology, 2022
Graphical AbstractSS, short stature; SDS, standard deviation scores; Control, normal height, n=30; ISS, idiopathic short stature n=31; GHD, short stature caused by growth hormone deficiency, n=29.
Guoyou Chen, Jinming Wang, Yisi Jing, Chunxiang Li, Wenyue Zhang, Shuang Yang, Ye Song, Xin Wang, Jincheng Liu, Dejun Yu, Zhichun Xu   +10 more
doaj   +1 more source

A new era of genetic diagnosis for short stature children: A review [PDF]

Precision and Future Medicine, 2022
Children with short stature are often presented to pediatric endocrinologists. Short stature is defined as the height that is more than two standard deviations below the corresponding mean height for a specific age and sex in a reference population ...
Yoo-Mi Kim
doaj   +1 more source

Estrogen Receptor 1 Gene Polymorphism and its Association with Idiopathic Short Stature in a North Indian Population [PDF]

J Clin Res Pediatr Endocrinol
Patel RS, Daniel R, Bhardwaj C, Kumari A, Bawa P, Tyagi A, Dayal D, Kaur A, Panigrahi I, Kaur H, Srivastava P.   +10 more
europepmc   +2 more sources

Idiopathic Short Stature: What to Expect from Genomic Investigations

Endocrines, 2023
Short stature is a common concern for physicians caring for children. In traditional investigations, about 70% of children are healthy, without producing clinical and laboratory findings that justify their growth disorder, being classified as having ...
Nathalia Liberatoscioli Menezes Andrade, Laurana Polli Cellin, Raissa Carneiro Rezende, Gabriela Andrade Vasques, Alexander Augusto Lima Jorge   +4 more
doaj   +1 more source

Investigating Novel Therapeutic Approaches for Idiopathic Short Stature: Targeting siRNA and Growth Hormone Delivery to the Growth Plate Using Exosome Nanoparticles. [PDF]

Adv Sci (Weinh)
Yuan J, Wang Y, Huang Y, Li S, Zhang X, Wu Z, Zhao W, Zhu J, Zhang J, Huang G, Yu P, Cheng X, Wang X, Liu X, Jia J.   +14 more
europepmc   +3 more sources

A study of short stature among adolescents in the rural tertiary center- A prospective observational study [PDF]

Al Ameen Journal of Medical Sciences, 2021
Background: Long-term morbidities during the adolescence period cause short stature which is permanent, once epiphysis fuse. Objectives: To evaluate etiology in short stature adolescents and its relation with HSDS (Height Standard Deviation Score) and BA
Dixa Shah, Sunil Pathak, Prasad Muley, Prashant Modi, Naveed M Ahmed, Vivek Bhatt   +5 more
doaj  

Levels and diagnostic values of serum visceral adipose tissue-derived serine protease inhibitor and secreted frizzle-related protein 5 in children with idiopathic short stature

Romanian Journal of Laboratory Medicine, 2023
Background: Idiopathic short stature (ISS) is a common type of short stature. We aimed to analyze the diagnostic values of serum visceral adipose tissue-derived serine protease inhibitor (Vaspin) and secreted frizzle-related protein 5 (SFRP5) for ISS ...
Che Ling, Chen Lei, Hou Binlan, Ouyang Fei, Zhou Huimei   +4 more
doaj   +1 more source

The Effect of The Height of a Second-Degree Relative on Children with Short Stature

Trends in Pediatrics, 2021
Objective: This study aimed to investigate the effect of the heights of second-degree relatives on adult height. Methods: This was a cross-sectional study.
Seda Yilmaz Semerci, Hasan Onal, Neval Topal, Rengin Siraneci   +3 more
doaj   +1 more source

Mucopolysaccharidosis Type I Disease Prevalence Among Patients With Idiopathic Short Stature in Saudi Arabia: Protocol for a Multicenter Cross-sectional Study

JMIR Research Protocols, 2021
BackgroundSince the underlying cause of idiopathic short stature can indeed be undiagnosed mucopolysaccharidosis type I, it is critical to identify patients with mucopolysaccharidosis type I among screened patients with idiopathic
Danyah Alsafadi, Aly Ezzat, Fatima Altamimi, Marwan ElBagoury, Mohammed Olfat, Mohammed Saleh, Sherif Roushdy, Yahia Aktham   +7 more
doaj   +1 more source