Results 41 to 50 of about 52,117 (235)

A Real-World Study of Recombinant Human Growth Hormone in the Treatment of Idiopathic Short Stature and Growth Hormone Deficiency

Therapeutics and Clinical Risk Management, 2022
Objective This study aimed to evaluate the clinical efficacy of recombinant human growth hormone (rhGH) in the treatment of children with idiopathic short stature (ISS) and growth hormone deficiency (GHD) and to explore the related factors affecting ...
Peng Gou, Xinran Cheng, Jie Leng, Na Su
semanticscholar   +1 more source

Chronic idiopathic hyperphosphatasia with unusual dental findings: a case report [PDF]

, 2012
Chronic idiopathic hyperphosphatasia(CIH) or juvenile Paget disease is believed to be a distinct disease characterized by an increase in the serum alkaline phosphatase, cortical thickening and bowing of the long bones, especially the femora. It is a rare
Gopakumar, Nair, Sreejan, Cheriya K., Subhas Babu, Gogineni   +2 more
core   +1 more source

Assessment and referral of patients with short stature by primary care physicians in the Arabian gulf region: Current perspectives from a regional survey

Frontiers in Pediatrics, 2022
Children with short stature are frequently referred late to pediatric endocrinologists in the Arabian Gulf region. This is likely a contributing factor to late initiation of treatment despite current evidence suggesting that children with short stature ...
W. Kaplan, E. Al Amiri, N. Attia, I. Al Basiri, I. Romany, E. Al Shehri, E. Al Shehri, A. Al Twaim, S. Al Yaarubi, A. Deeb, A. Deeb   +10 more
doaj   +1 more source

The measurement of health-related quality of life (QOL) in paediatric clinical trials: a systematic review [PDF]

, 2004
Background The goal of much care in chronic childhood illness is to improve quality of life (QOL). However, surveys suggest QOL measures are not routinely included.
Clarke, S., Eiser, C.
core   +3 more sources

LCN2 is a new diagnostic biomarker and potential therapeutic target in idiopathic short stature

Journal of Cellular and Molecular Medicine, 2022
Idiopathic short stature (ISS) is the most common paediatric endocrine disease. However, the underlying pathology of ISS remains unclear. Currently, there are no effective diagnostic markers or therapeutic strategies available for ISS.
Xijuan Liu, Jian Zhang, Jinghong Yuan, Rui Ding, Tao Liu, Jingyu Jia   +5 more
semanticscholar   +1 more source

Clinical Practice Pattern of Korean Medicine Doctors in Idiopathic Short Stature Treatment: A Survey Study

Evidence-Based Complementary and Alternative Medicine, 2022
Background Korean medicine (KM) interventions are attractive for children with idiopathic short stature (ISS). We investigated the real-world clinical practice patterns of KM doctors in ISS treatment.
Soobin Jang, Boram Lee
semanticscholar   +1 more source

Optimizing Patient Management and Adherence for Children Receiving Growth Hormone. [PDF]

, 2017
Poor adherence with growth hormone (GH) therapy has been associated with worse clinical outcomes, which in children relates specifically to their linear growth and loss of quality of life.
Carlo L. Acerini, Dagmar Lehwalder, Katarzyna Wac, Peter Bang   +3 more
core   +3 more sources

Association between uric acid and height during growth hormone therapy in children with idiopathic short stature

Frontiers in Endocrinology, 2022
Background Serum uric acid (UA) within appropriate levels is reported to be beneficial in patients with idiopathic short stature (ISS). This study aimed to evaluate the association between serum UA levels and height standard deviation scores (SDS) in ...
J. Yoon, Young-Jun Seo, E. Kwon, H. Lee, M. Kang, I. Hwang   +5 more
semanticscholar   +1 more source

Quality of Life of Short-Statured Children Born Small for Gestational Age or Idiopathic Growth Hormone Deficiency Within 1 Year of Growth Hormone Treatment

Frontiers in Pediatrics, 2019
Aside from clinical endpoints like height gain, health-related quality of life has also become an important outcome indicator in the medical field. However, the data on short stature and health-related quality of life is inconsistent.
Julia Quitmann, Janika Bloemeke, Neuza Silva, Neuza Silva, Monika Bullinger, Stefanie Witt, Ilker Akkurt, Desiree Dunstheimer, Christian Vogel, Volker Böttcher, Ursula Kuhnle Krahl, Markus Bettendorf, Eckhard Schönau, Susanne Fricke-Otto, Alexandra Keller, Klaus Mohnike, Helmuth-Günther Dörr   +16 more
doaj   +1 more source

Chinese herbal medicine for children with idiopathic short stature (ISS): A systematic review and meta-analysis

PLoS ONE, 2022
Background Idiopathic short stature (ISS) describes a heterogeneous group of children of many unidentified causes of short stature presently without definitive therapy.
Yingying Li, Xinying Chen, Zhengduo Liu, Jinghua Yang   +3 more
semanticscholar   +1 more source