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Idiopathic short stature (ISS) is a main reason for low height among children. Its exact aetiology remains unclear. Recent findings have suggested that the aberrant expression of circRNAs in peripheral blood samples is associated with many diseases ...
Xijuan Liu+5 more
semanticscholar +1 more source
Aside from clinical endpoints like height gain, health-related quality of life has also become an important outcome indicator in the medical field. However, the data on short stature and health-related quality of life is inconsistent.
Julia Quitmann+16 more
doaj +1 more source
Balanced assessment of growth disorders using clinical, endocrinological, and genetic approaches [PDF]
Determining the pathogenesis of pediatric growth disorders is often challenging. In many cases, no pathogenesis is identified, and a designation of idiopathic short stature is used.
Martin Oswald Savage, Helen Louise Storr
doaj +1 more source
GENETIC FEATURES OF CHILDREN WITH IDIOPATHIC SHORT STATURE
The aim: To investigate the clinical and genetic characteristics of children with idiopathic short stature, taking into account the polymorphism of the vitamin D receptor (VDR) BsmI gene. Materials and methods: Eighteen children diagnosed with of idiopathic short stature who were treated at the State Institution «V.P.
Mariana, Ryznychuk+4 more
openaire +2 more sources
The aim of the present study was to develop predictive models using clinical features and MRI texture features for distinguishing between growth hormone deficiency (GHD) and idiopathic short stature (ISS) in children with short stature.
Mengdi Cong+5 more
semanticscholar +1 more source
OBJECTIVES: To establish cut-off values for growth hormone concentrations using clonidine as a secretagogue and an immunochemiluminescent assay as the method of measurement and to analyze the response time as well as the influence of gender, nutritional ...
Maria de Fátima Borges+8 more
doaj +1 more source
A Novel Diagnostic Predictive Model for Idiopathic Short Stature in Children
Objective Idiopathic short stature (ISS), an endocrine-related disease, is difficult to diagnose. Previous studies have shown that many children with some inflammation-related diseases often have short stature, but whether inflammation is the underlying ...
Jinghong Yuan+6 more
semanticscholar +1 more source
The association between idiopathic scoliosis and growth hormone treatment in short children [PDF]
Purpose Idiopathic scoliosis is the most common form of scoliosis, and the risk of onset and progression has been found to correlate with growth spurts.
Mijin Park+6 more
doaj +1 more source
Analysis of A Case of Growth Retardation of Infants Caused By Maternal Medication During Lactation [PDF]
Short stature in childhood and even adulthood mostly originates from infancy and young children. It has been reported that 30.7% of children start to experience short stature before 6 months of age, 32.3% of children start to experience short stature ...
Zhang Junhua
doaj +1 more source
Controversies in the Definition and Treatment of Idiopathic Short Stature (ISS) [PDF]
The term idiopathic short stature (ISS) refers to short children with no identifiable disorder of the growth hormone (GH)/insulin like growth factor (IGF) axis and no other endocrine, genetic or organ system disorder. This heterogeneous group of short children without GH deficiency (GHD) includes children with constitutional delay of growth and puberty,
Pedicelli S+3 more
openaire +3 more sources