Results 61 to 70 of about 52,117 (235)
Pakistan Journal of Medical Sciences, 2022 Objective: To explore the significance of recombinant human growth hormone(rhGH) therapy in promoting the growth and development of children with idiopathic short stature (ISS).
Wenbiao Han +3 more
semanticscholar +1 more source
Phenotypic characterization of patients with deletions in the 3’-flanking SHOX region [PDF]
, 2013 Context. Leri–Weill dyschondrosteosis is a clinically variable skeletal dysplasia, caused by SHOX deletion or mutations, or a deletion of enhancer sequences in the 3’-flanking region.
Annemieke H. van der Hout +11 more
core +2 more sources
Idiopathic Short Stature - A Case Report
Bangladesh Journal of Child Health, 2023 Short stature in childhood is the most common reason for referral to pediatric endocrinologists. Idiopathic short stature is defined as ³2 SD below the corresponding mean height for a given age, sex, and population in a child with a normal birth size and normal body proportions and without evidence of any systemic, endocrine, nutritional, or ...
Suraiya Begum, Dhiraj Chandra Biswas
openaire +1 more source
Journal of Cellular and Molecular Medicine, 2021 Idiopathic short stature (ISS) is a main reason for low height among children. Its exact aetiology remains unclear. Recent findings have suggested that the aberrant expression of circRNAs in peripheral blood samples is associated with many diseases ...
Xijuan Liu +5 more
semanticscholar +1 more source
Safety Outcomes and Near-Adult Height Gain of Growth Hormone-Treated Children with SHOX Deficiency: Data from an Observational Study and a Clinical Trial [PDF]
, 2017 Background/Aims: To assess auxological and safety data for growth hormone (GH)-Treated children with SHOX deficiency. Methods: Data were examined for GH-Treated SHOX-deficient children (n = 521) from the observational Genetics and Neuroendocrinology of ...
Benabbad, I. (Imane) +10 more
core +1 more source
Ghrd3 polymorphism of growth hormone receptor gen in peruvian children with idiopathic short stature
Revista Peruana de Medicina Experimental y Salud Pública, 2016 Objectives. To describe the standardization of molecular detection and frequency of a growth hormone receptor gene deleted for exon three (GHRd3) polymorphism in a population of Peruvian children with idiopathic short stature.
Carlos Del Águila +5 more
doaj +1 more source
A Leri-Weill dyschondrosteosis patient confirmed by mutation analysis of gene [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2015 Leri-Weill dyschondrosteosis is characterized by SHOX deficiency, Madelung deformity, and mesomelic short stature. In addition, SHOX deficiency is associated with idiopathic short stature, Turner syndrome, and Langer mesomelic dysplasia.
Won Bok Choi +4 more
doaj +1 more source
Frontiers in Endocrinology, 2022 Background To evaluate the safety and efficacy of daily somatropin (Jintropin®), a recombinant human growth hormone, in prepubertal children with ISS in China. Methods This study was a multicenter, randomized, controlled, open-label, phase 3 study.
Jinna Yuan +11 more
semanticscholar +1 more source
Growth hormone therapy response in children with short stature
Egyptian Pediatric Association Gazette, 2023 Background Short stature is one of the main causes of children referral to pediatric endocrinologists. Common etiologies include idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA), and idiopathic short stature (ISS).
Amira Ahmed Gad +5 more
doaj +1 more source
JCRPE, 2022 ACAN variants can manifest as various clinical features, including short stature, advanced bone age (BA), and skeletal defects. Here, we report rare clinical manifestations of ACAN defects in a 9 year, 5 month-old girl born small for gestational age (SGA)
Su Ji Kim, Jong Seo Yoon, Il Tae Hwang
doaj +1 more source