Results 71 to 80 of about 52,117 (235)

Motives for choosing growth-enhancing hormone treatment in adolescents with idiopathic short stature: a questionnaire and structured interview study [PDF]

, 2005
Background Growth-enhancing hormone treatment is considered a possible intervention in short but otherwise healthy adolescents. Although height gain is an obvious measure for evaluating hormone treatment, this may not be the ultimate goal for the person,
A Erling, CAM de Wit, CS Holmes, D Mul, D Skuse, DE Sandberg, DE Sandberg, DE Sandberg, DE Sandberg, DE Sandberg, DE Sandberg, DE Sandberg, EM Lundgren, F Luteijn, FC Bakker, FC Verhulst, GA Kamp, Gerben Sinnema, Gerdine A Kamp, Hanneke Visser – van Balen, I van der Reijden-Lakeman, J Cohen, J Gilmour, J Huisman, Jaap Huisman, Jan M Wit, JH Kranzler, JL Ross, JW Veerman, LD Voss, LD Voss, LJ Gudas, M Fournier, M Gordon, M Lundgren, MA Connolly, MB Ranke, NC Theunissen, P Chatelain, P Siegel, PDA Treffers, PP Van Haassen, RA Richman, Rinie Geenen, RJ Honigman, RS Grew, SA Frankel, YK van Pareren   +47 more
core   +4 more sources

GH Resistance Is a Component of Idiopathic Short Stature: Implications for rhGH Therapy

Frontiers in Endocrinology, 2021
Idiopathic short stature (ISS) is a term used to describe a selection of short children for whom no precise aetiology has been identified. Molecular investigations have made notable discoveries in children with ISS, thus removing them from this category.
M. Savage, H. Storr
semanticscholar   +1 more source

De novo mutations in ARID1B associated with both syndromic and non-syndromic short stature [PDF]

, 2015
Supplementary data 2.
Andrew Dauber, Joel Hirschhorn, Lili Wang, RuEn Yao, Xiaodong Huang, Yanjie Fan, Yiping Shen, Yongguo Yu   +7 more
core   +4 more sources

Spondylocarpotarsal synostosis syndrome due to a novel loss of function FLNB variant: a case report

BMC Musculoskeletal Disorders, 2021
Background Loss of function or gain of function variants of Filamin B (FLNB) cause recessive or dominant skeletal disorders respectively. Spondylocarpotarsal synostosis syndrome (SCT) is a rare autosomal recessive disorder characterized by short stature,
Samina Yasin, Outi Makitie, Sadaf Naz
doaj   +1 more source

저신장 소아청소년의 임상적 접근

The Ewha Medical Journal, 2021
Growth represents a sentinel for general health state in children and adolescent. Linear growth in children and adolescent is a complex process influenced by numerous factors including genetic, prenatal, postnatal, and environmental factors.

doaj   +1 more source

A Novel Diagnostic Predictive Model for Idiopathic Short Stature in Children

Frontiers in Endocrinology, 2021
Objective Idiopathic short stature (ISS), an endocrine-related disease, is difficult to diagnose. Previous studies have shown that many children with some inflammation-related diseases often have short stature, but whether inflammation is the underlying ...
Jinghong Yuan, Z. Du, Zhiwen Wu, Yanqin Yang, Xigao Cheng, Xijuan Liu, Jingyu Jia   +6 more
semanticscholar   +1 more source

Heterozygous GHR gene mutation in a child with idiopathic short stature [PDF]

, 2017
Several monogenic defects have been reported to be associated with idiopathic short stature. Focusing on growth hormone receptor (GHR)-gene alterations, the heterozygosity of the same gene defect may be associated with a range of growth deficits.
Bozzola, Elena, Bozzola, Mauro, Meazza, Cristina, Messini, Beatrice, Mullis, Primus-E, Pagani, Sara, Petkovic, Vibor   +6 more
core  

Bird's-eye view of GnRH analog use in a pediatric endocrinology referral center [PDF]

, 2015
OBJECTIVE: Gonadotropin-releasing hormone analogs (GnRHa) are standard of care for the treatment of central precocious puberty (CPP). GnRHa have also been prescribed in other clinical settings with the hope of increasing adult stature, although ...
Eugster, Erica A., Greene, Ariana, Lewis, Katherine, Watson, Sara E.   +3 more
core   +1 more source

Children With Short Stature Display Reduced ACE2 Expression in Peripheral Blood Mononuclear Cells

Frontiers in Endocrinology, 2022
BackgroundThe cause of short stature remains often unknown. The renin-angiotensin system contributes to growth regulation. Several groups reported that angiotensin-converting enzyme 2 (ACE2)-knockout mice weighed less than controls.
Federica Tonon, Gianluca Tornese, Fabiola Giudici, Francesca Nicolardi, Barbara Toffoli, Egidio Barbi, Egidio Barbi, Bruno Fabris, Bruno Fabris, Stella Bernardi, Stella Bernardi   +10 more
doaj   +1 more source

Isolated Growth Hormone Deficiency and Idiopathic Short Stature: Comparative Efficiency after Growth Hormone Treatment up to Adult Height

Journal of Clinical Medicine, 2021
Introduction: Treatment with growth hormone (GH) is not approved for idiopathic short stature (ISS) in Europe. Objectives: To compare the growth of children treated with isolated GH deficiency (IGHD) vs. ISS-treated and untreated children.
Ana-Belen Ariza-Jiménez, I. Leiva Gea, M. J. Martínez-Aedo Ollero, J. López-Siguero   +3 more
semanticscholar   +1 more source