Results 121 to 130 of about 94,816 (308)
Serious Game iDO: Towards Better Education in Dementia Care
We describe the iDO serious game developed during implementation of the Innovative Digital Training Opportunities on Dementia for Direct Care Workers (IDO) project.
R. Maskeliūnas +6 more
semanticscholar +1 more source
Contract Labour, Job Quality and Turnover Intention—Evidence From Nigeria
ABSTRACT Labour contracting, where intermediaries provide farmers with migrant workers, plays a central role in meeting the demand for seasonal labour on labour‐intensive farms. Yet this system poses underresearched challenges for both workers and farmers.
Olayinka Aremu +3 more
wiley +1 more source
A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation [PDF]
Déborah Braun +2 more
openalex +1 more source
Tumour progression shows decrease in PD‐L1 expression in matched metastases/primary uveal melanomas
Abstract Purpose Immune checkpoint inhibitors (ICI) have revolutionised the treatment of several malignancies. However, the results of ICI therapy remain unsatisfactory in metastatic uveal melanoma (UM). We analysed the expression of PD1, PD‐L1, T‐cell and macrophage markers in a set of matched primary and metastatic UM in an attempt to better ...
Maria Chiara Gelmi +5 more
wiley +1 more source
Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez +6 more
wiley +1 more source
IDO expression in the brain: a double-edged sword [PDF]
Erik Kwidzinski, Ingo Bechmann
openalex +1 more source
Homoharringtonine (HHT) suppresses immune evasion in acute monocytic leukaemia (AML‐M5) by attenuating the FTO/m6A/LILRB4 axis, thereby enhancing CD8+ T cell cytotoxicity. ABSTRACT Acute monocytic leukaemia, a subtype of acute myeloid leukaemia (AML), is a highly aggressive malignancy characterised by a poor prognosis, primarily due to the ability of ...
Fangfang Huang +18 more
wiley +1 more source
Crystallization of heme dioxygenases IDO and TDO facilitates structure-based design of cancer immunology therapeutics [PDF]
Angela Oh
openalex +1 more source

