Results 151 to 160 of about 94,816 (308)
Necrostatin-1 blocks both RIPK1 and IDO: consequences for the study of cell death in experimental disease models [PDF]
, 2012 Peter Vandenabeele +3 more
openalex +1 more source
Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery
MedComm – Oncology, Volume 5, Issue 1, March 2026.This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem +9 more
wiley +1 more source
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
527 Digital spatial profiling of paired tumor biopsies reveals indoleamine 2,3-dioxygenase (IDO)1 as a potential resistance mechanism for a tumor-targeted 4–1BB agonist in patients with solid tumors [PDF]
, 2021 Tamara Tanos +9 more
openalex +1 more source
Cell and Gene Therapy in Equine Ocular Disease
Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.ABSTRACT Equine ocular disease is common and often challenging to treat using traditional methods. This has led to the development of new therapies. Like human medicine, veterinary medicine is adopting cellular and gene therapy as innovative approaches. Equine ocular disease is a particularly promising area for these techniques.
Kimberly A. S. Young +2 more
wiley +1 more source
Quantifying the Influence of Climate on Storm Activity Using Machine Learning
Geophysical Research Letters, Volume 53, Issue 3, 16 February 2026.Abstract Midlatitude storms vary due to the slowly evolving climate and the rapidly changing synoptic conditions. While the impact of both factors has been studied extensively, their relative contributions remain poorly quantified. We use 84 years of ERA‐5 reanalysis data and convolutional neural networks to assess the relative importance of seasonal ...
Or Hadas, Yohai Kaspi
wiley +1 more source