Results 171 to 180 of about 94,816 (308)
Anti-regulatory T cells are natural regulatory effector T cells
Niels Ødum
doaj +1 more source
Background: Organ transplantation program in developing countries is still significantly dwarfed. Health workers are undeniably important in the success of transplantation.
R Oluyombo +14 more
doaj
Indoleamine 2,3-Dioxygenase (IDO) [PDF]
Marina Scheler +5 more
openaire +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Design, Synthesis, and Structural Evolution of Pseudo‐Natural Product IDO1 Inhibitors and Degraders
The combination of bicyclic monoterpene‐ and pyrrolidine‐alkaloid fragments yields novel pseudo‐natural products. Biological characterization revealed that these iDegs are inhibitors and degraders of indoleamine‐2,3‐dioxygenase. Abstract Terpenoid alkaloids are derived from the fusion of structurally diverse terpenoid‐ and alkaloid moieties.
Xiu‐Fen Cheng +19 more
wiley +2 more sources
This systematic review and meta‐analysis (100 trials, 9192 patients) clarifies breast cancer ICI‐based combination toxicity hierarchies. ICI‐ADC has higher grade ≥ 3 TRAEs; ICI‐mTKI has the worst irAEs, while ICI‐PARPi/HER2‐targeted combinations present the lowest risks.
Yunwei Lu +4 more
wiley +1 more source
Strategies for enhancing food security and poverty status among women food entrepreneurs in Ido Local Government of Oyo State, Nigeria [PDF]
Adeyose Emmanuel Akinbola
openalex +1 more source

