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Plasma indoleamine-2,3-dioxygenase (IDO) is increased in drug-naïve major depressed patients and treatment with sertraline and ketoprofen normalizes IDO in association with pro-inflammatory and immune-regulatory cytokines.

CNS and Neurological Disorders - Drug Targets, 2020
BACKGROUND Major Depression Disorder (MDD) is accompanied by an immune response characterized by increased levels of inflammatory and immune-regulatory cytokines and stimulation of indoleamine-2,3-dioxygenase (IDO).
H. Al-Hakeim   +3 more
semanticscholar   +1 more source

iDO: Compiler-Directed Failure Atomicity for Nonvolatile Memory

Micro, 2018
This paper presents iDO, a compiler-directed approach to failure atomicity with nonvolatile memory. Unlike most prior work, which instruments each store of persistent data for redo or undo logging, the iDO compiler identifies idempotent instruction ...
Qingrui Liu   +5 more
semanticscholar   +1 more source

T lymphocytes to IDO+ cells: check

Blood, 2011
In this issue of Blood , Sorensen et al observe a functional indoleamine 2,3-dioxygenase (IDO)–specific CD8+ T-cell population in humans.[1][1] IDO-specific CD8+ T cells are capable of killing IDO+ cells.
Cailin Moira, Wilke, Weiping, Zou
openaire   +2 more sources

Tryptophan Catabolism in IDO+ Plasmacytoid Dendritic Cells

Current Drug Metabolism, 2007
Plasmacytoid dendritic cells (pDCs) represent a specialized cell population that produces large amounts of type I interferons, the so-called natural interferon-producing cells. Recently, murine and human pDCs have been credited with a unique ability to express indoleamine 2,3-dioxygenase (IDO) and to mediate immunosuppression in specific settings. This
FALLARINO, Francesca   +4 more
openaire   +3 more sources

Deletion of TDO2, IDO-1 and IDO-2 differentially affects mouse behavior and cognitive function

Behavioural Brain Research, 2016
Tryptophan, an amino acid involved in routine energy metabolism, is a key modulator of sickness behaviors associated with inflammatory states and also plays roles in some psychiatric disorders. Tissue concentrations of tryptophan are regulated primarily by the enzymes indoleamine 2,3-dioxygenase 1 (IDO1), IDO2 and tryptophan 2,3-dioxygenase (TDO ...
Lay Khoon Too   +6 more
openaire   +2 more sources

Indoleamine 2,3-dioxygenase (Ido) inhibitors and their nanomedicines for cancer immunotherapy.

Biomaterials, 2021
Yixuan Guo   +6 more
semanticscholar   +1 more source

???????????????????? ???????? ido ?? ???????????????????????????? ?????????????????? ?????????????? ?????????????????? ???????????? ?????????? ??????????????????????????????????????

2014
?????????????? ?????????????????????????? ????????????????????????????, ?????????????? ???????????? ?????????????????? ???????? ido, ?? ???????????????????????????? ?????????????????????? ???????????????? (??????) ?????????????????? ?????????????? (????) ?????????????? ?????????????? ???????????????? ???? ???? ?????????? ???????????? ???????????????? ??
openaire   +1 more source

?????????????? ???????????????????? ?????????? GATA-2 ?? IDO ?? ?????????????? ???????????????????? ???????????????????????? ???????????????????????????????????????? ?????????????????? ???????????? ???????????? ???????????? ????????????????

2014
The expression rate of gata2 and ido genes was comparatively studied in general suspension and in isolated by magnet sorting hemopoietic and mesenchymal stem cell fractions of fetal liver of the mice of the14th and 18th gestation days after cryopreservation. There was demonstrated the expression rate of gata2 and ido genes in fetal liver cells with the
openaire   +1 more source

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