Results 21 to 30 of about 94,816 (308)

Assessment of Willingness to pay for Community-Based Health Insurance among Artisans in a selected Community of Ekiti State, Southwest Nigeria

Ibom Medical Journal, 2022
Background: Community-based health insurance (CBHI) has emerged as a more efficient and equitable approach to healthcare financing. It was designed to ensure that sufficient resources are made available for members to access effective healthcare.
Elegbede OE, Durowade KA, Sanni TA, Ipinnimo TM, Alabi AK   +4 more
doaj   +1 more source

A community survey of the pattern and determinants of household sources of energy for cooking in rural and urban south western, Nigeria

The Pan African Medical Journal, 2012
BACKGROUND: The use of solid fuels for cooking is associated with indoor pollution and lung diseases. The objective of the study was to determine the pattern and determinants of household sources of energy for cooking in rural and urban South Western ...
Olufemi Olumuyiwa Desalu, Ololade Olusola Ojo, Ebenezer Kayode Ariyibi, Tolutope Fasanmi Kolawole, Ayodele Idowu Ogunleye   +4 more
doaj   +1 more source

Awareness and practice of self breast examination among female nurses at the Federal Teaching Hospital Ido-Ekiti, Nigeria

Journal of Public Health in Africa, 2016
Breast cancer is the most common female malignancy linked with high levels of morbidity and mortality in developing countries due to delayed diagnosis. This research assessed the knowledge of signs and risk factors of breast cancer and practice of self ...
Olusegun Emmanuel Gabriel, Oluwaserimi Adewumi Ajetunmobi, Olabode Muftau Shabi, Olaide Toyin Elegbede, Raymond Akujuobi Okere, Olusegun Adesola Busari, Ayokunle Samuel Dada   +6 more
doaj   +1 more source

Comparison of Serum Calcium Level in Preeclamptic and Normotensive Pregnant Women in Ekiti State, Nigeria

SVU - International Journal of Medical Sciences, 2023
Background: Pre-eclampsia is often referred to as disease of theories as the precise factors involved in its pathogenesis are unclear. While alterations in calcium metabolism have been linked with preeclampsia, the role of calcium in the development of ...
Francis Bamijoko Adejube, Adeniyi Augustine Adebayo, Caroline Oluseyi Adejube, Omolara Adepate Olaleye, Abiola Olukayode Olaleye*   +4 more
doaj   +1 more source

CD4 responses against IDO [PDF]

OncoImmunology, 2012
Natural indoleamine-2,3-dioxygenase (IDO)-reactive CD4(+) T cells have been shown to release interferonγ (IFNγ), tumor necrosis factor α (TNFα), as well as interleukin 17 (IL-17). In some individuals, these cells also demonstrated the ability to suppress IL-10 production.
openaire   +2 more sources

Indoleamine 2,3‐dioxygenase (IDO)‐1 and IDO‐2 activity and severe course of COVID‐19

Journal of Pathology, 2021
COVID‐19 is a pandemic with high morbidity and mortality. In an autopsy cohort of COVID‐19 patients, we found extensive accumulation of the tryptophan degradation products 3‐hydroxy‐anthranilic acid and quinolinic acid in the lungs, heart, and brain ...
Lihui Guo, B. Schurink, E. Roos, E. Nossent, J. Duitman, A. Vlaar, P. Van Der Valk, F. Vaz, S. Yeh, Zachary Geeraerts, A. Dijkhuis, L. V. van Vught, M. Bugiani, R. Lutter, Michiel Anne Geke Brent Frank Diane Martijn Harm Jan Marij van Agtmael Algera Appelman van Baarle Bax Beudel , M. V. van Agtmael, A. G. Algera, B. Appelman, F. V. van Baarle, D. Bax, M. Beudel, H. Bogaard, M. Bomers, P. Bonta, L. Bos, M. Botta, J. de Brabander, G. Bree, S. de Bruin, M. Bugiani, E. Bulle, O. Chouchane, A. Cloherty, Buis T.P. Buis, M. D. de Rotte, M. Dijkstra, D. Dongelmans, R. Dujardin, P. Elbers, L. Fleuren, S. Geerlings, T. Geijtenbeek, A. Girbes, B. Goorhuis, M. Grobusch, F. Hafkamp, L. Hagens, J. Hamann, V. Harris, R. Hemke, S. Hermans, L. Heunks, M. Hollmann, J. Horn, J. Hovius, M. D. de Jong, R. Koning, E. Lim, N. van Mourik, J. Nellen, E. Nossent, F. Paulus, E. Peters, D. Piña-Fuentes, T. van der Poll, B. Preckel, J. Prins, J. Raasveld, T. Reijnders, M. Schinkel, F. Schrauwen, M. Schultz, A. Schuurmans, Jaap Schuurmans, K. Sigaloff, M. Slim, M. Smit, C. Stijnis, W. Stilma, C. Teunissen, P. Thoral, A. Tsonas, A. Tsonas, M. van der Valk, D. Veelo, C. Volleman, H. D. de Vries, L. Vught, M. van Vugt, D. Wouters, A. Zwinderman, M. Brouwer, W. Wiersinga, A. Vlaar, D. van de Beek   +94 more
semanticscholar   +1 more source

Dysregulation of the Tryptophan Pathway Evidences Gender Differences in COPD

Metabolites, 2019
Increased activity of indoleamine 2,3-dioxygenase (IDO) and tryptophan hydroxylase (TPH) have been reported in individuals with chronic obstructive pulmonary disease (COPD).
Shama Naz, Maria Bhat, Sara Ståhl, Helena Forsslund, C. Magnus Sköld, Åsa M. Wheelock, Craig E. Wheelock   +6 more
doaj   +1 more source

Impact of extended-release niacin on immune activation in HIV-infected immunological non-responders on effective antiretroviral therapy

HIV Research & Clinical Practice, 2020
Background Background: Tryptophan (Trp) catabolism into immunosuppressive kynurenine (Kyn) is involved in immune dysregulation during HIV infection. Niacin (vitamin B3) could control the excess of tryptophan depletion and represents a potential strategy ...
Bertrand Lebouché, Alexis Yero, Tao Shi, Omar Farnos, Joel Singer, Ido Kema, Cecilia T. Costiniuk, Réjean Thomas, Marie-Josée Brouillette, Kim Engler, Jean-Pierre Routy, Mohammad-Ali Jenabian, for the CTN PT006 Study Group   +12 more
doaj   +1 more source

Immunostimulatory and Immunodynamic Modeling Analysis to Determine a Plausible Starting Dose of mRNA-4359 for Use in First-In-Human Trials. [PDF]

CPT Pharmacometrics Syst Pharmacol
ABSTRACT The investigational antigen‐specific immunotherapy mRNA‐4359 is a lipid nanoparticle–encapsulated mRNA‐based immunotherapy that encodes for the immunogenic indoleamine 2,3‐dioxygenase (IDO) and programmed death‐ligand 1 (PD‐L1) antigens.
Greene SA, Channavazzala M, Paleja B, Sandhu HS, Kumar R, Attarwala H, Van L, Liang M.   +7 more
europepmc   +2 more sources

Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment

Cell Death and Differentiation, 2020
Clinical response to immunotherapy is closely associated with the immunosuppressive tumour microenvironment (TME), and influenced by the dynamic interaction between tumour cells and lymphatic endothelial cells (LECs).
Chenfei Zhou, Yanmei Zhang, Ruiming Yan, Lei Huang, A. Mellor, Yang Yang, Xiaojing Chen, Wenfei Wei, Xiangguang Wu, Lan Yu, Luojiao Liang, Dan Zhang, Sha Wu, Wei Wang   +13 more
semanticscholar   +1 more source