Results 71 to 80 of about 94,816 (308)
Sultan Qaboos University Medical Journal, 2013 Acute dystonic reactions (ADR) are extrapyramidal effects that usually occur after the initiation of a wide variety of drugs or triggering factors besides neuroleptics.
Olusegun A. Busari +5 more
doaj
Elder abuse among older persons in a local government area in southwest Nigeria: A cross-sectional study [PDF]
Journal of Research in Clinical MedicineIntroduction: Elder abuse is a major but subtle social problem affecting millions of older adults globally. Nigeria, a developing nation with about 4% of her 200000000 population being older persons is not left out.
Oladele Ademola Atoyebi +7 more
doaj +1 more source
Awake craniotomy in a Covid-19 positive patient: The challenges and outcome
Interdisciplinary Neurosurgery, 2021 Background: The SARS-COV-2 is a novel coronavirus which is the etiological agent of the COVID-19 infection. The neurosurgical practice is not exempted from the impact of the COVID-19 pandemic.
Abiodun Idowu Okunlola
doaj +1 more source
Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment
Advanced Science, EarlyView.This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang +7 more
wiley +1 more source
Eos, Transactions American Geophysical Union, 1980 For the 1970's, the International Decade of Ocean Exploration (IDOE) began as a legislative, foreign policy, and geopolitical undertaking. It ended short of its goals. E. Wenk, Jr., is quoted as saying‘… IDOE…failed to head off international conflict over intensified use of the sea by using collaborative exploration as a new and untainted means to ...
openaire +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Advanced Intelligent Discovery, EarlyView.Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
Journal of Basic and Applied Research in Biomedicine, 2022 G6PD deficiency is known to be associated with neonatal jaundice, kernicterus and even death. G6PD is the first enzyme of the pentose phosphate pathway and catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconolactone, with the concomitant ...
Omisakin C. T +3 more
doaj +2 more sources
Cell Death and Differentiation, 2017 Mesenchymal stem cells (MSCs) have been demonstrated to be anti-inflammatory against various immune disorders through several factors, including indoleamine 2,3-dioxygenase (IDO) and TNF-stimulated gene 6 (TSG-6).
Guan Wang +9 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2020 Objective: Indoleamin-2,3-dioxygenase-1 (IDO) has been identified as a checkpoint protein involved in generating the immunosuppressive tumor microenvironment that supports tumor growth.
Jun-bao Liu +4 more
semanticscholar +1 more source