Intraocular penetration of penciclovir after oral administration of famciclovir: a population pharmacokinetic model [PDF]
Objectives We developed a population model that describes the ocular penetration and pharmacokinetics of penciclovir in human aqueous humour and plasma after oral administration of famciclovir.
Baglivo, Edoardo +6 more
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Discovery of Broad-Spectrum Antiviral Agents by Drug Repurposing for Rapid Response to Emergent Viral Pandemics: Building Digital Tools to Advance Translational Research [PDF]
The ongoing COVID-19 pandemic caused by the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in 2019 has highlighted urgency for a more efficient and comprehensive paradigm for antiviral development.
Yao, Rouan
core
Corneal Opacification in Infancy [PDF]
The purpose of this paper is to present a systematic classification of the more important conditions that can manifest as corneal opacification in early infancy and to state its differential diagnostic ...
Ching, Florencio C.
core +1 more source
The susceptibility of pathogenic free-living amebae to chemotherapeutic agents : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]
The treatment of infections caused by pathogenic free-living amebae (PFLA) has, until only recently, been far from successful. The continued screening of chemotherapeutic agents against amebae of the genera Naegleria and Acanthamoeba is therefore of the ...
Donald, Jennifer Jane
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Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management [PDF]
Drug induced cicatrizing conjunctivitis (DICC) is defined as a disease in which conjunctival cicatrization develops as a response to the chronic use of inciting topical and, rarely, systemic medications.
Basu, Sayan +6 more
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Investigation of the in vitro inhibitory mechanisms of quercetin on varicella-zoster virus [PDF]
摘要 【目的】 1、应用水痘-带状疱疹病毒(VZV)报告细胞系MV9G细胞从植物药成分中筛选具有抑制VZV作用的物质。 2、应用VZV报告细胞系MV9G研究槲皮素体外抑制VZV作用及其机制。 【方法】 1、植物药成分的细胞毒性试验:MV9G细胞分别在含有丁子香酚、桑色素、姜黄素、杨梅酮和槲皮素的培养基中培养72hrs后测定MV9G细胞的ATP含量,根据药物对MV9G细胞ATP含量的影响分析药物的细胞毒性,并计算植物药成分对MV9G细胞的半数致死浓度(CD50)。 2、植物药成分对VZV半数抑制浓度测定 ...
廉成翔
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dissertationDiseases associated with some of the human herpes viruses have been recognized for centuries; these include fever blisters or herpes labialis, herpes genitalis, varicella and zoster. It is only within the past decade or two that the impact of
Hamill, Mary Lou
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Idoxuridine in Herpes Zoster. [PDF]
V. Esmann, K.E. Wildenhoff
+7 more sources
The assessment on cross immunity with smallpox virus and antiviral drug sensitivity of the isolated mpox virus strain WIBP-MPXV-001 in China. [PDF]
Zeng Y +16 more
europepmc +1 more source
"Treatment-Resistance" to Idoxuridine in Herpetic Keratitis
Whenever a new antimicrobial drug has been used on a large scale in medical treatment, the selection pressure exerted by that drug has favored the emergence of drugresistant microbial variants. Failure of clinical treatment has often been the first indication of the emergence of drug resistance.
V R, Coleman, E, Tsu, E, Jawetz
openaire +2 more sources

