Results 41 to 50 of about 1,980 (168)

Nanoparticle Skin Penetration: Depths and Routes Modeled In‐Silico

open access: yesSmall, Volume 21, Issue 20, May 19, 2025.
An in‐silico human skin model based on 20 years of NP penetration studies, incorporating 19 parameters is developed. Using random forest and Kennard‐Stone sorting, the model achieves 95% accuracy, identifying hair follicle diameter as the dominant penetration factor.
Natsumi Maeda   +7 more
wiley   +1 more source

Antivirals in COVID‐19: A Focus on Pediatric Cardiac Patients

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
The COVID‐19 pandemic created an unprecedented public health crisis, driven by its rapid global spread and the urgent need for worldwide collaborative interventions to contain it. This urgency spurred the search for therapeutic agents to prevent or manage the infection.
Dalia Safi   +4 more
wiley   +1 more source

Macrodendritic ulcerative keratitis and conjunctival lymphoid hyperplasia in horses with equine herpesvirus‐2 and equine herpesvirus‐5 infections

open access: yesVeterinary Ophthalmology, Volume 27, Issue 3, Page 277-285, May 2024.
Abstract Objective The aim of this study was to describe the clinical, confocal microscopic, histologic, and virologic features of horses with macrodendritic ulcerative keratitis and conjunctival lymphoid hyperplasia associated with equine herpesvirus‐2 and equine herpesvirus‐5 infection.
Eric C. Ledbetter   +2 more
wiley   +1 more source

Eficacia del oleozón en el tratamiento de la gingivoestomatitis herpética aguda en pacientes pediátricos

open access: yesCorreo Científico Médico, 2012
Se realizó una evaluación económica completa del tipo costo-eficacia para determinar la eficacia del oleozón versus idoxuridina en el tratamiento de la gingivoestomatitis herpética aguda en edad pediátrica, basados en los resultados de un estudio ...
Osmar Rodríguez Corona   +1 more
doaj  

Antimicrobial peptides for novel antiviral strategies in the current post‐COVID‐19 pandemic

open access: yesJournal of Peptide Science, Volume 30, Issue 1, January 2024.
This review describes the main physicochemical characteristics of antimicrobial peptides, with particular focus on peptides derived from amphibian skin. Summarizing the various antiviral activities of these peptides and the underlying mechanism, this review emphasizes the high potential of these small molecules for the development of new antiviral ...
Maria Rosa Loffredo   +3 more
wiley   +1 more source

Poxvirus infections in dermatology – the neglected, the notable, and the notorious

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 1, Page 56-93, January 2024.
Summary The family Poxviridae currently comprises 22 genera that infect vertebrates. Of these, members of the Ortho‐, Para‐, Mollusci‐ and Yatapoxvirus genera have been associated with human diseases of high clinical relevance in dermatology. Historically, smallpox had been a notorious health threat until it was declared eradicated by the World Health ...
Patrick E. Obermeier   +2 more
wiley   +1 more source

Antiviral Activity of Nitazoxanide and Miltefosine Against FeHV‐1 In Vitro

open access: yesVeterinary Medicine International, Volume 2024, Issue 1, 2024.
Feline herpesvirus type 1 (FeHV‐1) is a primary pathogen in cats responsible for respiratory and ocular signs. There are presently no antiviral drugs that are officially licensed for veterinary use in several countries. Consequently, veterinarians must depend on off‐label antivirals designed for human use. Recent advances in virus–host cell interaction
Consiglia Longobardi   +8 more
wiley   +1 more source

Ganciclovir ophthalmic gel 0.15% for the treatment of acute herpetic keratitis: background, effectiveness, tolerability, safety, and future applications

open access: yesTherapeutics and Clinical Risk Management, 2014
Timothy Y Chou, Bennett Y Hong Department of Ophthalmology, Stony Brook University, Stony Brook, NY, USA Abstract: Eye disease due to herpes simplex virus (HSV) is a leading cause of ocular morbidity and the number one infectious cause of unilateral ...
Chou TY, Hong BY
doaj  

"Treatment-Resistance" to Idoxuridine in Herpetic Keratitis

open access: yesExperimental Biology and Medicine, 1968
Whenever a new antimicrobial drug has been used on a large scale in medical treatment, the selection pressure exerted by that drug has favored the emergence of drugresistant microbial variants. Failure of clinical treatment has often been the first indication of the emergence of drug resistance.
V R, Coleman, E, Tsu, E, Jawetz
openaire   +2 more sources

The assessment on cross immunity with smallpox virus and antiviral drug sensitivity of the isolated mpox virus strain WIBP-MPXV-001 in China. [PDF]

open access: yesEmerg Microbes Infect, 2023
Zeng Y   +16 more
europepmc   +1 more source

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