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Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

Advanced Science, EarlyView.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu, Xiaoxu Wang, Shun Li, Xuxin Li, Pengfei Du, Yameng Zheng, Lu Liu, Yanyan Zhang, Omri Wurtzel, Guofeng Cheng   +9 more
wiley   +1 more source

Peanut genome resource: a functional genomics platform for Arachis hypogaea. [PDF]

Plant Cell Physiol
Yang CW, Chow CN, Chen H, Tseng KC, Wu NY, Zhuang Y, Zhuang W, Chang WC.   +7 more
europepmc   +1 more source

Boron-doped diamond solution-gate field-effect transistor (BDD-SGFET) biosensor for gene mutation detection. [PDF]

Microsyst Nanoeng
Lin Z, Zheng Y, Chen Y, Wang C, Yuan Z.
europepmc   +1 more source

Proteomic datasets of three <i>Hermetia illucens</i> Larvae Forms (Fresh, Dried, and Protein concentrate). [PDF]

Data Brief
Abdel-Moneim AE, Tomas D, Labas V, Méda B, Réhault-Godbert S.   +4 more
europepmc   +1 more source

DC-FusionGNN: A Dual-Channel Framework Integrating Global Self-Attention and Local Topology Learning for Identifying Key Resistance Genes Against <i>Fusarium graminearum</i> Infection in Maize. [PDF]

Plants (Basel)
Dai Y, Qiao M, Fan J, Lu S, Zhao E, Zhu Y, Liu H, Zhang H.   +7 more
europepmc   +1 more source

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Id gene expression during development and molecular cloning of the human Id-1 gene

Molecular Brain Research, 1995
Id genes encode helix-loop-helix proteins that inhibit transcription by forming inactive heterodimers with basic helix-loop-helix (bHLH) proteins. bHLH proteins normally form either homodimers or heterodimers with other bHLH proteins and bind to a DNA sequence element activating transcription. Id-containing heterodimers are inactive because Id proteins
W, Zhu, J, Dahmen, A, Bulfone, M, Rigolet, M C, Hernandez, W L, Kuo, L, Puelles, J L, Rubenstein, M A, Israel   +8 more
openaire   +2 more sources

Id genes and proteins as promising targets in cancer therapy

Trends in Molecular Medicine, 2004
Since the identification of Id proteins more than a decade ago, much work has demonstrated their regulatory roles in development, cell fate and lineage determination, proliferation, differentiation, angiogenesis, invasion and migration. Recent studies reveal not only that Id protein expression is significantly correlated both with cancer progression ...
Sylvia, Fong, Robert J, Debs, Pierre-Yves, Desprez   +2 more
openaire   +2 more sources

Polymorphism of the murine inhibitor of differentiation-controlling gene, Id

Gene, 1995
The structure of Id was examined by Southern analysis in inbred mouse lines which included five subspecies of Mus musculus. No variation was detected within this species. The species Mus cookii shares the same form found in mice of M. musculus derivation, indicative of a long evolutionary history and a common origin.
S A, Marlow, P H, Kay, J M, Papadimitriou   +2 more
openaire   +2 more sources