Results 11 to 20 of about 12,364 (188)
Hot-wiring dynein-2 establishes roles for IFT-A in retrograde train assembly and motility
Summary: Intraflagellar transport (IFT) trains, built around IFT-A and IFT-B complexes, are carried by opposing motors to import and export ciliary cargo.
Francisco Gonçalves-Santos +6 more
doaj +1 more source
IFT‐81 and IFT‐74 are required for intraflagellar transport in C. elegans [PDF]
Intraflagellar transport (IFT) is essential machinery for biogenesis and maintenance of cilia in many eukaryotic and prokaryotic cells. A large number of polypeptides are known to be involved in IFT, but the physiological role of each component is not fully elucidated. Here, we identified a C.
Tetsuo, Kobayashi +4 more
openaire +2 more sources
This study introduces a new framework to quantify the wettability of powdered carbonate rock from existing correlations between zeta potential and contact angle.
Sina Rezaei Gomari +4 more
doaj +1 more source
Background The aim of this study was to decompose independent effects of age, period, and cohort on trends in outpatient addiction care utilization resulting from alcohol (AUD) and illicit substances use disorders (ISUD).
Sara Specht +5 more
doaj +1 more source
Background Despite the decline in cigarette smoking prevalence during nearly the past two decades, tobacco use is still widespread in the German adult population, accounting for 125,000 deaths each year and causing tremendous social costs.
Simone Delle +5 more
doaj +1 more source
Differential diagnostics of bullous dermatoses
Bullous dermatoses are the diseases characterized by vesication and erosion of skin and/or mucos coats, production of autoantibodies against the structural components of epidermis and/or derma. The most frequent diseases of these disorders are pemphigus,
A. A. Kubanov +2 more
doaj +1 more source
Building train carriages for ciliary transport: (IFT-)A complex task
Cilia assembly and function require intraflagellar transport (IFT), a mechanism that uses “trains” to transport cargoes into and out of cilia. While much has been learned about IFT in the past decades, IFT train assembly, loading of cargo and transport ...
Francisco Gonçalves-Santos +3 more
doaj +1 more source
Our research reveals that the deletion of WDR-31, RP-2, and ELMD-1 is leading to ciliary accumulation of IFT Complex B components and KIF17 kinesin. In conclusion, WDR31, ELMOD, and RP2 are working in regulating IFT via the BBSome.
Sebiha Cevik +15 more
doaj +1 more source
TULP4, a novel E3 ligase gene, participates in neuronal migration as a candidate in schizophrenia
Mutations identified from four SCZ pedigrees resulted in decreased TULP4 expression. Tulp4 knockdown caused delayed neuron migration in embryonic mice, and impaired cognition and prepulse inhibition in adult mice. These phenotypes may be related to TULP4 through its involvement in the formation of a novel E3 ubiquitin ligases.
Yan Bi +19 more
wiley +1 more source
Applications of nanoparticles (NPs) in the Enhanced oil recovery (EOR) method has become a major research field as nanoparticles are found to be able to interfere with the interfacial tension and wettability of multiphase fluids within the reservoir ...
Zhen Yin Lau +3 more
doaj +1 more source

