Results 11 to 20 of about 185,112 (228)
Assembly and mother centriole recruitment of IFT-B subcomplexes to form IFT-B holocomplex
Cell Structure and FunctionFor the biogenesis and maintenance of cilia, bidirectional protein trafficking within cilia is crucial, and is conducted by intraflagellar transport (IFT) trains containing the IFT-A and IFT-B complexes that are powered by dynein-2 and kinesin-II motors.
Koshi Tasaki +3 more
doaj +3 more sources
The molecular structure of IFT-A and IFT-B in anterograde intraflagellar transport trains
Nature Structural & Molecular Biology, 2023 Abstract Anterograde intraflagellar transport (IFT) trains are essential for cilia assembly and maintenance. These trains are formed of 22 IFT-A and IFT-B proteins that link structural and signaling cargos to microtubule motors for import into cilia.
Samuel E. Lacey +2 more
openaire +2 more sources
IFT‐81 and IFT‐74 are required for intraflagellar transport in C. elegans [PDF]
Genes to Cells, 2007 Intraflagellar transport (IFT) is essential machinery for biogenesis and maintenance of cilia in many eukaryotic and prokaryotic cells. A large number of polypeptides are known to be involved in IFT, but the physiological role of each component is not fully elucidated. Here, we identified a C.
Tetsuo, Kobayashi +4 more
openaire +2 more sources
Energies, 2020 This study introduces a new framework to quantify the wettability of powdered carbonate rock from existing correlations between zeta potential and contact angle.
Sina Rezaei Gomari +4 more
doaj +1 more source
TULP4, a novel E3 ligase gene, participates in neuronal migration as a candidate in schizophrenia
CNS Neuroscience &Therapeutics, EarlyView., 2023 Mutations identified from four SCZ pedigrees resulted in decreased TULP4 expression. Tulp4 knockdown caused delayed neuron migration in embryonic mice, and impaired cognition and prepulse inhibition in adult mice. These phenotypes may be related to TULP4 through its involvement in the formation of a novel E3 ubiquitin ligases.
Yan Bi +19 more
wiley +1 more source
BMC Public Health, 2022 Background The aim of this study was to decompose independent effects of age, period, and cohort on trends in outpatient addiction care utilization resulting from alcohol (AUD) and illicit substances use disorders (ISUD).
Sara Specht +5 more
doaj +1 more source
BMC Public Health, 2022 Background Despite the decline in cigarette smoking prevalence during nearly the past two decades, tobacco use is still widespread in the German adult population, accounting for 125,000 deaths each year and causing tremendous social costs.
Simone Delle +5 more
doaj +1 more source
The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length [PDF]
, 2018 Axonemal dyneins, including inner dynein arm I1, assemble in the cytoplasm prior to transport into cilia by intraflagellar transport (IFT). How I1 dynein interacts with IFT is not understood.
Alford, Lea M +14 more
core +2 more sources
Energies, 2019 Applications of nanoparticles (NPs) in the Enhanced oil recovery (EOR) method has become a major research field as nanoparticles are found to be able to interfere with the interfacial tension and wettability of multiphase fluids within the reservoir ...
Zhen Yin Lau +3 more
doaj +1 more source
Building train carriages for ciliary transport: (IFT-)A complex task
Communications Biology, 2023 Cilia assembly and function require intraflagellar transport (IFT), a mechanism that uses “trains” to transport cargoes into and out of cilia. While much has been learned about IFT in the past decades, IFT train assembly, loading of cargo and transport ...
Francisco Gonçalves-Santos +3 more
doaj +1 more source