Results 211 to 220 of about 173,132 (261)
Exploration of the mechanism of Xinjiang Rosa laxa Retz.Fruit extract on IgA nephropathy by bioinformatics and machine learning methods. [PDF]
Bioresour BioprocessQianqian F +5 more
europepmc +1 more source
Levofloxacin-associated leukocytoclastic vasculitis with bullous lesions in a man treated for a diabetic foot infection. [PDF]
IDCasesKhazan A, Kanduri S, Black K, Ricotti C.
europepmc +1 more source
Complement factor H supplementation rather than complete C3 knockout provides therapeutic benefits in IgA nephropathy. [PDF]
Mol BiomedLi X +8 more
europepmc +1 more source
The Role of IgA in the Pathogenesis of IgA Nephropathy [PDF]
International Journal of Molecular Sciences, 2019 Immunoglobulin A (IgA) is the most abundant antibody isotype produced in humans, predominantly present in the mucosal areas where its main functions are the neutralization of toxins, prevention of microbial invasion across the mucosal epithelial barrier, and simultaneous maintenance of a physiologically indispensable symbiotic relationship with ...
Martina Perse, Željka Večerić-Haler
exaly +4 more sources
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Trends in Immunology, 2001
IgA has traditionally been regarded a non-inflammatory antibody. This might indeed be true for secretory IgA (SIgA), which exerts its function at mucosal surfaces where commensal microorganisms and dietary antigens prevail. Serum IgA, however, potently triggers (pro)-inflammatory activity upon binding to the myeloid IgA receptor, FcalphaRI.
Gestur Vidarsson +2 more
exaly +5 more sources
IgA has traditionally been regarded a non-inflammatory antibody. This might indeed be true for secretory IgA (SIgA), which exerts its function at mucosal surfaces where commensal microorganisms and dietary antigens prevail. Serum IgA, however, potently triggers (pro)-inflammatory activity upon binding to the myeloid IgA receptor, FcalphaRI.
Gestur Vidarsson +2 more
exaly +5 more sources
Role of macromolecular IgA in IgA nephropathy [PDF]
Kidney International, 2005 Primary IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis, leading to progressive renal failure in almost one third of the patients. The disease is characterized by mesangial deposits of IgA. The pathogenesis of IgAN remains incompletely understood.
Cees Van Kooten, Johan W de Fijter
exaly +3 more sources
Nature Reviews Disease Primers, 2016 Globally, IgA nephropathy (IgAN) is the most common primary glomerulonephritis that can progress to renal failure. The exact pathogenesis of IgAN is not well defined, but current biochemical and genetic data implicate overproduction of aberrantly glycosylated IgA1.
Francesco Paolo Schena +2 more
exaly +9 more sources
Serum IgA Class Anti-IgA Antibody in IgA Nephropathy
Nephron, 2008IgA class anti-IgA antibody was sought by an immunoabsorbent technique in sera from patients with IgA nephropathy (IgA-N, n = 62), other forms of primary glomerulonephritis (PGN, n = 41), seropositive rheumatoid arthritis (RF-positive, n = 18) and normal controls (c, n = 50).
Y, Hiki, M, Saitoh, Y, Kobayashi
openaire +2 more sources