Results 231 to 240 of about 254,581 (301)

Early HHV-6 IgG and IgA responses during acute SARS-CoV-2 infection in relation to long COVID: a multicohort observational study. [PDF]

EBioMedicine
Choudhury A, Burry MJ, Kwon WJ, Yin X, Rallistan A, Presti S, Ndakwah GS, Cheng EQ, Kalaycioglu M, Harris M, Frankovich J, Karlson EW, Bollyky J, Utz PJ, Prestwood TR.   +14 more
europepmc   +1 more source

MCL‐1 inhibition triggers a largely reversible cardiac stress signature in a humanised mouse model

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Myeloid cell leukaemia‐1 (MCL‐1) is an essential anti‐apoptotic protein and a promising therapeutic target in oncology. Early clinical studies of MCL‐1 inhibitors reported unexpected elevations in cardiac troponin, raising concerns about potential cardiotoxicity.
Markus B. Heckmann, Zsanett Papdi, Nils J. Strauch, Daniel Finke, Marc‐Steffen Raab, Antje Blank, Norbert Frey, Lorenz H. Lehmann   +7 more
wiley   +1 more source

Sarsasapogenin Preserves Podocyte Integrity and Attenuates Renal Injury in Experimental IgA Nephropathy. [PDF]

FASEB J
Kumaş M, Canlar Akar D, Gül M, Karadaş E, Kum Özşengezer S, Kulualp K, Yavuz O, Yilmaz O.   +7 more
europepmc   +1 more source

Dupilumab in Cholinergic Urticaria: An Exploratory Phase 2 Investigator‐Initiated Study

Allergy, EarlyView.
Annika Gutsche, Weronika Grabowska, Sabine Altrichter, Eva Grekowitz, Stephanie Roll, Guido Heine, Petra Staubach, Wolfgang Pfützner, Randolf Brehler, Andrea Bauer, Nicola Wagner, Gerda Wurpts, Pascale Salameh, Ali Salehzadeh‐Yazdi, Samad S. Jahandideh, Martin Metz   +15 more
wiley   +1 more source

Compound‐Heterozygous PLVAP Missense Variants Associated With Attenuated Protein‐Losing Enteropathy (DIAR10)

Clinical Genetics, EarlyView.
A three‐year‐old girl with attenuated protein‐losing enteropathy carried compound‐heterozygous missense PLVAP variants inherited from unaffected non‐consanguineous parents. The case supports residual PLVAP function in missense‐associated DIAR10 and expands its genetic and clinical spectrum.
Jana Zídková, Dagmar Procházková, Petra Konečná, Kamila Réblová, Tereza Kramářová, Johana Kopčilová, Magdaléna Soukup Vodičková, Romana Borská, Lenka Fajkusová   +8 more
wiley   +1 more source

Vectored Immunoprophylaxis for Mucosal Immunity: Advances and Challenges Associated with Recombinant Secretory IgA Expression. [PDF]

Vaccines (Basel)
Manchester BJ, Gommerman JL, Sharif S, Susta L, Wootton SK.   +4 more
europepmc   +1 more source

Volume Quantization with Flexible Singularities for Hexahedral Meshing

Computer Graphics Forum, EarlyView.
Abstract We present a novel algorithm for quantization and subsequent hexahedral mesh generation from seamless volumetric maps. Quantization is the process of choosing integers that represent the numbers of hexahedral elements to be placed in each region of the volume, and transforming the seamless map into an integer‐grid map matching that choice ...
H. Brückler, M. Campen
wiley   +1 more source

Case Report: Advanced IgA nephropathy with psoriasis and a complex clinicopathologic course. [PDF]

Front Nephrol
Wang L, Li M, Xu B, Shu D.
europepmc   +1 more source

Fibrillar‐Type Dermatitis Herpetiformis: An Underrecognized Variant That Is Rarely Associated With Celiac Disease and Lacking Epidermal Transglutaminase Deposition: A Report of Two Cases

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Dermatitis herpetiformis (DH) is a rare, intensely pruritic cutaneous manifestation of celiac disease (CD), typically presenting with excoriated papulovesicular lesions on extensor surfaces. DH is associated with IgA autoantibodies against epidermal transglutaminase (eTG), which form granular immune deposits in the papillary dermis and induce ...
Jeffrey Damman, Elodie Mendels, Sven van der Woude, Sharon Veenbergen, Gilles F. H. Diercks, Martijn B. van Doorn   +5 more
wiley   +1 more source