Results 191 to 200 of about 31,703 (224)
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AUTOIMMUNITY IN IgA NEPHROPATHY
The Lancet, 1988IgG autoantibodies with specificity for glomerular antigenic determinants have been detected in the sera of 23 of 75 patients with IgA nephropathy. The antigen or antigens are distinct from the Goodpasture antigen and have at least three components that bind IgG.
F W, Ballardie +3 more
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Biomarkers in Medicine, 2014
IgA nephropathy is the most common primary glomerulonephritis and presents with gross hematuria and upper respiratory infection, with slow progression to end-stage renal disease in up to 50% of affected patients. Kidney biopsies are the gold standard method of diagnosis and frequently are not performed as the majority of individuals are asymptomatic ...
Vicki J, Hwang +3 more
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IgA nephropathy is the most common primary glomerulonephritis and presents with gross hematuria and upper respiratory infection, with slow progression to end-stage renal disease in up to 50% of affected patients. Kidney biopsies are the gold standard method of diagnosis and frequently are not performed as the majority of individuals are asymptomatic ...
Vicki J, Hwang +3 more
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Pathophysiology of IgA Nephropathy
Advances in Anatomic Pathology, 2017Immunoglobulin (Ig)A nephropathy is the most prevalent primary chronic glomerular disease in the world. Studies of molecular and cellular interactions involved in the pathogenesis of IgA nephropathy have revealed several inherent abnormalities in the production and subsequent handling of IgA1. In patients with this disease, altered glycan structures in
Turki, Al Hussain +3 more
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The genetics of IgA nephropathy
Nature Clinical Practice Nephrology, 2007IgA nephropathy is the most common form of primary glomerulonephritis. Variations in clinical manifestations indicate that a diagnosis of IgA nephropathy encompasses multiple disease subsets that cannot be distinguished on the basis of renal pathology or clinical variables alone.
Isabel, Beerman +4 more
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BioDrugs, 1998
IgA nephropathy is the commonest form of glomerulonephritis worldwide, and is one of the major causes of terminal renal failure in most industrialised countries. It is defined by the dominance of IgA mesangial deposits in immunofluorescence studies. Corticosteroid-sensitive nephrosis lipoides (minimal change disease) with IgA deposits and superimposed ...
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IgA nephropathy is the commonest form of glomerulonephritis worldwide, and is one of the major causes of terminal renal failure in most industrialised countries. It is defined by the dominance of IgA mesangial deposits in immunofluorescence studies. Corticosteroid-sensitive nephrosis lipoides (minimal change disease) with IgA deposits and superimposed ...
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The pathogenesis of IgA nephropathy
Current Opinion in Nephrology & Hypertension, 2011This review will analyze contemporary information concerning the possible pathogenetic mechanisms involved in IgA nephropathy, emphasizing studies in humans rather than experimental animals.Deposition of IgA in the glomeruli, the hallmark of IgA nephropathy, may be a quite common phenomenon.
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British Journal of Hospital Medicine, 2014
Ck, Cheung, S, Bashir, J, Barratt
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Ck, Cheung, S, Bashir, J, Barratt
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