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Background: We have shown previously that human desmocollin (Dsc) 1 is recognized by IgA autoantibodtes of subcorneal pustular dermatosis (SPD) type IgA pemphigus.
Takashi Hashimoto +2 more
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Clinics in Dermatology, 2011
Pemphigus is a life-threatening autoimmune blistering disease. Pemphigus is divided into 4 major types; pemphigus vulgaris, pemphigus foliaceus, paraneoplastic pemphigus, and IgA pemphigus. Among them, IgA pemphigus is characterized by tissue-bound and circulating IgA antibodies targeting desmosomal or nondesmosomal cell surface components in the ...
Daisuke, Tsuruta +11 more
openaire +3 more sources
Pemphigus is a life-threatening autoimmune blistering disease. Pemphigus is divided into 4 major types; pemphigus vulgaris, pemphigus foliaceus, paraneoplastic pemphigus, and IgA pemphigus. Among them, IgA pemphigus is characterized by tissue-bound and circulating IgA antibodies targeting desmosomal or nondesmosomal cell surface components in the ...
Daisuke, Tsuruta +11 more
openaire +3 more sources
<i>Background:</i> While subcorneal pustular dermatosis-type IgA pemphigus shows subcorneal pustules, intra-epidermal neutrophilic dermatosis (IEN)-type IgA pemphigus is characterised by pustule formation throughout the entire epidermis.
Hirohiko Sueki +2 more
exaly +2 more sources
The American Journal of Dermatopathology, 2014
IgG/IgA pemphigus has recently been described in the literature as an overlap of pemphigus vulgaris or pemphigus foliaceus with IgA pemphigus. There has also been some postulation that this IgG/IgA pemphigus may be associated with internal malignancy as well.
Natalie, Lane, Palak, Parekh
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IgG/IgA pemphigus has recently been described in the literature as an overlap of pemphigus vulgaris or pemphigus foliaceus with IgA pemphigus. There has also been some postulation that this IgG/IgA pemphigus may be associated with internal malignancy as well.
Natalie, Lane, Palak, Parekh
openaire +2 more sources
Journal of the American Academy of Dermatology, 1991
24. Jimbow K, Fitzpatrick TB, Szabo G, et aI. Congenital circumscribed hypomelanosis; a characterization based on electron microscopic study of tuberous sclerosis, nevus depigmentosus, and piebaldism. J Invest Dermatol 1975; 64:50-62. 25. Tibbles lA, Cohen MM Jr. The Proteus syndrome: the Elephant Man diagnosed. Br Med J Clin Res 1986;293: 683-5.
R. Caputo +7 more
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24. Jimbow K, Fitzpatrick TB, Szabo G, et aI. Congenital circumscribed hypomelanosis; a characterization based on electron microscopic study of tuberous sclerosis, nevus depigmentosus, and piebaldism. J Invest Dermatol 1975; 64:50-62. 25. Tibbles lA, Cohen MM Jr. The Proteus syndrome: the Elephant Man diagnosed. Br Med J Clin Res 1986;293: 683-5.
R. Caputo +7 more
openaire +3 more sources
The American Journal of Dermatopathology, 2013
Pyodermatitis-pyostomatitis vegetans (PPV) constitutes an inflammatory mucocutaneous dermatosis that is associated with inflammatory bowel disease. Clinically, PPV appears as pustules on mucosal surfaces and as vegetating exudative plaques on intertriginous surfaces. It is typically a clinical diagnosis supported by histological findings.
Michael M, Wolz +3 more
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Pyodermatitis-pyostomatitis vegetans (PPV) constitutes an inflammatory mucocutaneous dermatosis that is associated with inflammatory bowel disease. Clinically, PPV appears as pustules on mucosal surfaces and as vegetating exudative plaques on intertriginous surfaces. It is typically a clinical diagnosis supported by histological findings.
Michael M, Wolz +3 more
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Immunopathology of IgA pemphigus
Clinics in Dermatology, 2001Cases with vesiculo-pustular skin lesions showing anti-keratinocyte cell surface autoantibodies of exclusively IgA class have been identified.1–19 Although these cases were reported under a number of different names, the term “IgA pemphigus” is now used most commonly. In 1982, Wallach et al. first described a case demonstrating IgA deposition diffusely
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IgA pemphigus foliaceus with a clinical presentation of pemphigus herpetiformis
Journal of the American Academy of Dermatology, 1991A patient with clinical features of herpetiform pemphigus of the foliaceus type had histologic findings consistent with pemphigus. Intercellular IgA deposits in a pattern like that of IgG in pemphigus were present. Circulating pemphigus-type IgA-class antibodies reacted first only with guinea pig and later in the disease also with monkey esophagus ...
T P, Chorzelski +7 more
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IgA Pemphigus foliaceus: A Case Report
Dermatologica, 2009An 84-year-old male with a 4-week history of vesiculobullous eruptions was diagnosed clinically and pathologically to suffer from pemphigus foliaceus. Amazingly, direct immunofluorescence demonstrated intercellular IgA deposits in the whole epidermis. The patient did not respond to a regimen of fluocortolone and azathioprine but rapidly improved under ...
D, Zillikens +3 more
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